From the FDA Drug Label
DOSAGE AND ADMINISTRATION ... For treatment of pain or primary dysmenorrhea the recommended dosage is 50 mg three times a day ... For the relief of osteoarthritis, the recommended dosage is 100-150 mg/day in divided doses, 50 mg twice a day or three times a day ... For the relief of rheumatoid arthritis, the recommended dosage is 150-200 mg/day in divided doses, 50 mg three times a day or four times a day. The dosage for Sporolac DS (assuming it is a formulation of diclofenac) is not directly stated in the provided label, but based on the information for diclofenac potassium tablets, the recommended dosages are:
- Pain or primary dysmenorrhea: 50 mg three times a day
- Osteoarthritis: 100-150 mg/day in divided doses
- Rheumatoid arthritis: 150-200 mg/day in divided doses 1
From the Research
The recommended dosage for Sporolac DS is one sachet or capsule twice daily, preferably after meals, as it helps maintain healthy gut flora and may reduce the risk of gastrointestinal complications, particularly in patients taking nonsteroidal anti-inflammatory drugs (NSAIDs) like diclofenac, as seen in studies such as 2.
Key Considerations
- The dosage may vary depending on the condition being treated, with typical treatment durations ranging from 1-2 weeks for acute digestive issues to several months for chronic conditions.
- It is essential to take the supplement regularly at the same times each day and store it in a cool, dry place to ensure optimal effectiveness.
- Patients taking NSAIDs, such as diclofenac, should be aware of the potential risk of gastrointestinal bleeding, as highlighted in studies like 3 and 2.
- The use of proton pump inhibitors (PPIs) with NSAIDs may increase the risk of lower gastrointestinal bleeding, as shown in 2, whereas the use of mucoplective agents may not pose a significant risk, as seen in the same study.
Important Factors
- Age and diclofenac medication were found to be significant risk factors for upper gastrointestinal bleeding in gout patients, as reported in 3.
- The risk of lower gastrointestinal bleeding was significantly higher in NSAID+PPI users than in NSAID-only users, as demonstrated in 2.
- Patients should consult their healthcare provider if they experience any unusual symptoms while taking Sporolac DS, particularly if they are taking NSAIDs or have a history of gastrointestinal complications.