What is the cause of fever in a 42-year-old man with morbid obesity, type 2 diabetes mellitus (T2DM), and hypertension, on the second postoperative day after elective laparoscopic ventral hernia repair with mesh, presenting with mild abdominal tenderness and tachycardia?

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Differential Diagnosis for Postoperative Fever

The patient's presentation with fever on the second postoperative day after an elective laparoscopic ventral hernia repair with mesh requires a thorough differential diagnosis. The following categories outline potential causes:

  • Single Most Likely Diagnosis
    • Atelectasis: This is a common cause of postoperative fever, especially in patients who have undergone general anesthesia and have risk factors such as morbid obesity. Atelectasis can lead to decreased lung volumes and impaired gas exchange, which may not always present with significant respiratory symptoms early on.
  • Other Likely Diagnoses
    • Surgical Site Infection (SSI): Although the surgical incisions are clean and dry without purulent drainage, early SSI can present with minimal signs of infection. The presence of a wound drain with serosanguineous fluid could be a risk factor.
    • Urinary Tract Infection (UTI): Despite the urinary catheter being removed in the operating room, the patient could still be at risk for UTI, especially if the catheter was in place for an extended period or if there were any issues with the catheterization process.
    • Pneumonia: Postoperative pneumonia is a concern, particularly in patients with risk factors such as morbid obesity and recent general anesthesia. The patient's lungs are clear, but early pneumonia might not have significant findings on physical examination.
  • Do Not Miss Diagnoses
    • Mesh Infection: Infection of the mesh used in hernia repair is a serious complication that can present with non-specific symptoms, including fever. Early recognition is crucial for appropriate management.
    • Bowel Injury: A bowel injury during laparoscopic surgery can lead to peritonitis and sepsis. Although the abdomen is described as soft and non-distended, any signs of peritoneal irritation or sepsis would necessitate immediate intervention.
    • Deep Vein Thrombosis (DVT) or Pulmonary Embolism (PE): These are potentially life-threatening conditions that can occur postoperatively, especially in patients with risk factors such as morbid obesity and recent surgery. Fever can be a presenting symptom of PE.
  • Rare Diagnoses
    • Adrenal Insufficiency: This could be considered in patients who have been on long-term corticosteroids, although there's no mention of this in the patient's history. Fever can be a symptom of adrenal insufficiency.
    • Drug Fever: This is a rare cause of fever but can occur with any medication, including antibiotics. The patient's recent surgery and potential postoperative medications could be contributing factors.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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