Treatment of Chronic Myofascial Back Pain
Begin with a structured exercise program as the foundation of treatment, combined with heat therapy and manual therapies, reserving pharmacologic interventions for inadequate response to these first-line nonpharmacologic approaches. 1, 2
Initial Nonpharmacologic Treatment (Weeks 0-6)
Exercise Therapy (Primary Treatment)
- Implement a supervised exercise program incorporating stretching, strengthening, and motor control exercises. 1, 2 Exercise therapy demonstrates good evidence of moderate efficacy and should be the cornerstone of treatment for chronic myofascial back pain. 3, 1
- Motor control exercise (MCE) specifically targets restoration of coordination, control, and strength of spinal-supporting muscles, moderately decreasing pain scores and improving function in short- to long-term follow-up. 3, 2
- The specific type of exercise matters less than patient adherence—different exercise regimens show similar effectiveness. 2
Heat Therapy
- Apply superficial heat (heat wraps) for moderate pain relief and disability reduction. 3, 2 Moderate-quality evidence shows heat wraps moderately improve pain at 5 days and disability at 4 days compared to placebo. 3
- Combining heat with exercise provides greater pain relief than exercise alone. 3, 2
Manual Therapies
- Incorporate massage therapy, which shows moderate effectiveness for chronic myofascial back pain. 1, 4
- Deep tissue massage, myofascial release techniques, and spray-and-stretch methods target trigger points characteristic of myofascial pain. 4, 5
- Spinal manipulation provides moderate effectiveness for pain relief and functional improvement. 1, 2
Additional Nonpharmacologic Options
- Consider acupuncture or dry needling for trigger point treatment. 3, 4 Fair evidence supports acupuncture's effectiveness for chronic low back pain. 3
- Cognitive-behavioral therapy demonstrates good evidence of moderate efficacy for addressing psychosocial factors that complicate chronic myofascial pain. 3, 1
- Yoga (particularly Iyengar yoga) results in moderately lower pain scores and improved function at 24 weeks compared to usual care. 3, 1
- Tai chi produces moderate pain improvement compared to wait-list controls. 3, 1
Pharmacologic Treatment (If Inadequate Response After 4-6 Weeks)
First-Line Pharmacologic Therapy
- Add NSAIDs (naproxen or ibuprofen) as first-line pharmacologic therapy. 1, 6 The American College of Physicians recommends NSAIDs for patients with inadequate response to nonpharmacologic therapy. 1
- Topical NSAIDs or topical lidocaine can be applied directly to painful trigger point areas. 3
Muscle Relaxants (Adjunctive)
- Consider short-term cyclobenzaprine (5-10 mg three times daily) as an adjunct to rest and physical therapy for relief of muscle spasm. 7 Cyclobenzaprine is FDA-approved for acute, painful musculoskeletal conditions and should be used only for short periods (up to 2-3 weeks). 7
- Cyclobenzaprine produces clinical improvement whether or not sedation occurs, though dry mouth is the most frequent adverse reaction. 7
Second-Line Pharmacologic Therapy
- Add tramadol or duloxetine (starting at 30 mg daily, titrating to 60 mg daily) if NSAIDs provide inadequate response. 1, 6
- Tricyclic antidepressants (amitriptyline 10-25 mg at bedtime) can be considered as part of a multimodal strategy. 3, 1
Advanced Interventions (If Refractory After 8-12 Weeks)
Procedural Interventions
- Refer to pain management for trigger point injections, which physically denervate the neural loop of the trigger point. 4, 5, 8
- Consider dry needling or onabotulinumtoxinA injections for persistent trigger points. 4, 8
- Low-level laser therapy combined with NSAIDs largely decreases pain intensity and moderately improves function. 3
Multidisciplinary Rehabilitation
- Refer for intensive multidisciplinary rehabilitation combining physical, psychological, and educational interventions. 1 Good evidence supports interdisciplinary rehabilitation as moderately effective for chronic low back pain. 3
Opioids (Last Resort Only)
- Consider opioids only after documented failure of all other therapies and only when potential benefits clearly outweigh risks. 1, 6 This requires thorough discussion of risks including substance use disorder screening. 6
Critical Pitfalls to Avoid
- Do not prescribe bed rest—it leads to deconditioning and worsens outcomes. 1, 6 Emphasize remaining active. 6
- Avoid routine imaging for nonspecific myofascial back pain—findings are often nonspecific and do not improve outcomes. 1, 6
- Do not use TENS—it shows no difference compared to sham TENS for pain intensity or function. 1, 2
- Avoid lumbar supports—they have not shown clear benefits for chronic back pain. 3, 2
- Strongly avoid interventional procedures such as epidural injections, radiofrequency ablation, and joint injections—these lack evidence of benefit. 6
- Recognize that cyclobenzaprine is indicated only for acute conditions (up to 2-3 weeks) and has not been found effective for spasticity. 7
Expected Outcomes and Realistic Expectations
The magnitude of pain benefits from nonpharmacologic therapies is typically small to moderate (10-20 points on a 100-point visual analogue pain scale, or 2-4 points on the Roland-Morris Disability Questionnaire). 3, 1 Effects on function are generally smaller than effects on pain. 1 Symptoms often resolve with early intervention, but as myofascial pain enters the chronic stage, it becomes increasingly refractory to treatment. 4, 5