What are the treatment options for chronic myofascial back pain?

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Last updated: November 12, 2025View editorial policy

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Treatment of Chronic Myofascial Back Pain

Begin with a structured exercise program as the foundation of treatment, combined with heat therapy and manual therapies, reserving pharmacologic interventions for inadequate response to these first-line nonpharmacologic approaches. 1, 2

Initial Nonpharmacologic Treatment (Weeks 0-6)

Exercise Therapy (Primary Treatment)

  • Implement a supervised exercise program incorporating stretching, strengthening, and motor control exercises. 1, 2 Exercise therapy demonstrates good evidence of moderate efficacy and should be the cornerstone of treatment for chronic myofascial back pain. 3, 1
  • Motor control exercise (MCE) specifically targets restoration of coordination, control, and strength of spinal-supporting muscles, moderately decreasing pain scores and improving function in short- to long-term follow-up. 3, 2
  • The specific type of exercise matters less than patient adherence—different exercise regimens show similar effectiveness. 2

Heat Therapy

  • Apply superficial heat (heat wraps) for moderate pain relief and disability reduction. 3, 2 Moderate-quality evidence shows heat wraps moderately improve pain at 5 days and disability at 4 days compared to placebo. 3
  • Combining heat with exercise provides greater pain relief than exercise alone. 3, 2

Manual Therapies

  • Incorporate massage therapy, which shows moderate effectiveness for chronic myofascial back pain. 1, 4
  • Deep tissue massage, myofascial release techniques, and spray-and-stretch methods target trigger points characteristic of myofascial pain. 4, 5
  • Spinal manipulation provides moderate effectiveness for pain relief and functional improvement. 1, 2

Additional Nonpharmacologic Options

  • Consider acupuncture or dry needling for trigger point treatment. 3, 4 Fair evidence supports acupuncture's effectiveness for chronic low back pain. 3
  • Cognitive-behavioral therapy demonstrates good evidence of moderate efficacy for addressing psychosocial factors that complicate chronic myofascial pain. 3, 1
  • Yoga (particularly Iyengar yoga) results in moderately lower pain scores and improved function at 24 weeks compared to usual care. 3, 1
  • Tai chi produces moderate pain improvement compared to wait-list controls. 3, 1

Pharmacologic Treatment (If Inadequate Response After 4-6 Weeks)

First-Line Pharmacologic Therapy

  • Add NSAIDs (naproxen or ibuprofen) as first-line pharmacologic therapy. 1, 6 The American College of Physicians recommends NSAIDs for patients with inadequate response to nonpharmacologic therapy. 1
  • Topical NSAIDs or topical lidocaine can be applied directly to painful trigger point areas. 3

Muscle Relaxants (Adjunctive)

  • Consider short-term cyclobenzaprine (5-10 mg three times daily) as an adjunct to rest and physical therapy for relief of muscle spasm. 7 Cyclobenzaprine is FDA-approved for acute, painful musculoskeletal conditions and should be used only for short periods (up to 2-3 weeks). 7
  • Cyclobenzaprine produces clinical improvement whether or not sedation occurs, though dry mouth is the most frequent adverse reaction. 7

Second-Line Pharmacologic Therapy

  • Add tramadol or duloxetine (starting at 30 mg daily, titrating to 60 mg daily) if NSAIDs provide inadequate response. 1, 6
  • Tricyclic antidepressants (amitriptyline 10-25 mg at bedtime) can be considered as part of a multimodal strategy. 3, 1

Advanced Interventions (If Refractory After 8-12 Weeks)

Procedural Interventions

  • Refer to pain management for trigger point injections, which physically denervate the neural loop of the trigger point. 4, 5, 8
  • Consider dry needling or onabotulinumtoxinA injections for persistent trigger points. 4, 8
  • Low-level laser therapy combined with NSAIDs largely decreases pain intensity and moderately improves function. 3

Multidisciplinary Rehabilitation

  • Refer for intensive multidisciplinary rehabilitation combining physical, psychological, and educational interventions. 1 Good evidence supports interdisciplinary rehabilitation as moderately effective for chronic low back pain. 3

Opioids (Last Resort Only)

  • Consider opioids only after documented failure of all other therapies and only when potential benefits clearly outweigh risks. 1, 6 This requires thorough discussion of risks including substance use disorder screening. 6

Critical Pitfalls to Avoid

  • Do not prescribe bed rest—it leads to deconditioning and worsens outcomes. 1, 6 Emphasize remaining active. 6
  • Avoid routine imaging for nonspecific myofascial back pain—findings are often nonspecific and do not improve outcomes. 1, 6
  • Do not use TENS—it shows no difference compared to sham TENS for pain intensity or function. 1, 2
  • Avoid lumbar supports—they have not shown clear benefits for chronic back pain. 3, 2
  • Strongly avoid interventional procedures such as epidural injections, radiofrequency ablation, and joint injections—these lack evidence of benefit. 6
  • Recognize that cyclobenzaprine is indicated only for acute conditions (up to 2-3 weeks) and has not been found effective for spasticity. 7

Expected Outcomes and Realistic Expectations

The magnitude of pain benefits from nonpharmacologic therapies is typically small to moderate (10-20 points on a 100-point visual analogue pain scale, or 2-4 points on the Roland-Morris Disability Questionnaire). 3, 1 Effects on function are generally smaller than effects on pain. 1 Symptoms often resolve with early intervention, but as myofascial pain enters the chronic stage, it becomes increasingly refractory to treatment. 4, 5

References

Guideline

Treatment of Chronic Low Back Pain

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Chronic Back Pain with Muscle Spasm Treatment

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Chronic Low Back Pain in Older Adults

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Myofascial pain syndrome treatments.

Physical medicine and rehabilitation clinics of North America, 2014

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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