What does a calcium score of 2307 indicate?

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Last updated: November 12, 2025View editorial policy

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What a Calcium Score of 2307 Means

A calcium score of 2307 indicates severe coronary atherosclerosis with extremely high cardiovascular risk—this score places you in the highest risk category (>1000) with approximately 17.9% risk of death or myocardial infarction and warrants immediate aggressive medical management and screening for silent ischemia. 1

Understanding Your Score

Your calcium score of 2307 represents an extraordinarily high burden of calcified atherosclerotic plaque in your coronary arteries:

  • Risk magnitude: Patients with calcium scores ≥1000 have a 58-fold higher risk of cardiac events compared to those with zero calcium 1
  • Absolute risk: The overall rate of death or myocardial infarction is approximately 17.9% for scores ≥1000, significantly higher than 13.3% for scores 401-1000 1
  • Comparison: Your score far exceeds the threshold of 400, which already indicates severe disease 2, 3

What This Score Tells Us

Atherosclerosis burden: The degree of coronary calcification correlates directly with total atherosclerotic plaque burden—your score of 2307 indicates extensive coronary atherosclerosis affecting multiple vessels 4

Important caveat: While calcium scoring definitively confirms atherosclerosis, it does not directly measure the degree of arterial narrowing (stenosis). The specificity for detecting ≥50% stenosis is only 50% 4. However, at your extremely elevated score, the presence of significant atherosclerotic disease is unequivocal 5.

Immediate Clinical Actions Required

Screening for silent ischemia: The American College of Cardiology and American Heart Association recommend screening for clinically silent ischemia when calcium scores exceed 400—your score of 2307 makes this mandatory 6, 1

Stress testing: You should undergo stress myocardial perfusion imaging (MPI) for advanced cardiovascular risk assessment, as this is specifically recommended for patients with CAC ≥400 1

Aggressive medical therapy: Your score mandates intensive preventive interventions including:

  • High-intensity statin therapy 4
  • Aggressive blood pressure control 4
  • Antiplatelet therapy consideration 4
  • Comprehensive cardiovascular risk factor modification 4

Risk Stratification Context

Multi-vessel disease: Mortality increases substantially as the number of vessels with calcification increases, especially with 2-vessel and 3-vessel disease, which is highly likely at your score level 4

Left main involvement: If any of your calcification involves the left main coronary artery (LMCA), mortality risk increases by 40% when >25% of total calcium is in the LMCA 4

Long-term prognosis: Studies with up to 15-year follow-up demonstrate that cardiovascular risk increases proportionally with calcium scores, with scores >300 showing a 10-fold increase in coronary heart disease events 2, 7

Critical Pitfalls to Avoid

Do not assume all calcification equals obstruction: While your score confirms severe atherosclerosis, functional testing is needed to determine which lesions are causing ischemia and require intervention 1

Do not delay evaluation: At this score level, you are at very high risk for acute coronary events and require urgent cardiology evaluation—this is not a "wait and see" situation 1, 3

Do not rely on symptoms alone: Many patients with severe coronary calcification remain asymptomatic until they experience a major cardiac event 8

Next Steps

You need immediate referral to cardiology for:

  • Stress myocardial perfusion imaging to detect silent ischemia 1
  • Consideration of coronary angiography if stress testing is positive 1
  • Initiation or intensification of aggressive medical therapy 4, 1
  • Comprehensive cardiovascular risk factor assessment and management 4

References

Guideline

Coronary Artery Calcium Score > 1000: Implications and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

CT Calcium Score for Diagnosing Atherosclerotic Cardiovascular Disease

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

CT Calcium Scoring for Cardiovascular Risk Assessment

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Coronary Calcium Score and Cardiovascular Risk.

Journal of the American College of Cardiology, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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