What CPT (Current Procedural Terminology) code covers a lipid panel for Medicare coverage?

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Last updated: November 12, 2025View editorial policy

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CPT Code for Medicare Lipid Panel Coverage

Medicare covers lipid panel testing using CPT code 80061, which includes measurement of total cholesterol, HDL cholesterol, triglycerides, and calculated LDL cholesterol.

Standard Lipid Panel Components

The comprehensive lipid profile covered by Medicare includes 1, 2:

  • Total cholesterol
  • LDL cholesterol (calculated or direct)
  • HDL cholesterol
  • Triglycerides

CPT Code 80061 Specifications

CPT code 80061 is the standard code for a complete lipid panel that encompasses all four measurements listed above 1. This code is recognized by Medicare for reimbursement when medically necessary.

Fasting vs. Non-Fasting Samples

  • Either fasting or non-fasting samples are acceptable for initial lipid assessment and cardiovascular risk estimation in adults 1, 2
  • If non-fasting triglycerides are ≥400 mg/dL (≥4.5 mmol/L), a repeat fasting lipid profile should be obtained for accurate assessment 1
  • Non-fasting samples provide sufficient accuracy for most clinical decision-making regarding cardiovascular risk 1

Medicare Coverage Frequency

Based on guideline recommendations that inform Medicare coverage policies 1:

  • Initial screening: Recommended for all adults ≥20 years of age
  • Routine monitoring: Every 5 years for patients with normal lipid profiles and low cardiovascular risk 1, 2
  • More frequent testing (every 3-12 months) is appropriate for patients on lipid-lowering therapy or those with established cardiovascular disease 1

Additional Testing Considerations

While not part of the standard CPT 80061 panel, non-HDL cholesterol (calculated as total cholesterol minus HDL cholesterol) is an important secondary parameter that requires no additional testing or cost 2, 3. This value is automatically available from the standard lipid panel results.

Common Pitfalls to Avoid

  • Do not use CPT 80061 for individual lipid component testing - separate codes exist for single analyte measurements
  • Ensure medical necessity documentation is present in the patient record to support Medicare coverage
  • For LDL-C <70 mg/dL (<1.8 mmol/L), direct LDL-C measurement may be more accurate than the Friedewald calculation, though this may require a different CPT code 1, 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Interpreting Lipid Profiles for Cardiovascular Risk Assessment

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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