Does olmesartan (Olmetec) affect Prostate-Specific Antigen (PSA) test results?

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From the Research

Olmesartan does not affect PSA test results. Olmesartan is an angiotensin II receptor blocker (ARB) used to treat high blood pressure, and it works by relaxing blood vessels to lower blood pressure. PSA tests measure a protein produced by the prostate gland, and are used to screen for prostate cancer or monitor prostate conditions. Unlike some medications such as finasteride or dutasteride (5-alpha reductase inhibitors) which can lower PSA levels by approximately 50%, olmesartan has no known mechanism to interfere with PSA production or measurement.

The provided evidence does not directly address the effect of olmesartan on PSA test results. However, based on the pharmacological properties of olmesartan, as described in 1, it is unlikely to affect PSA levels. The studies provided, such as 2, 3, 4, and 5, discuss various topics related to prostate cancer screening, digital rectal examination, and antihypertensive medications, but do not provide specific information on the effect of olmesartan on PSA test results.

If you're taking olmesartan and need a PSA test, you can continue your medication as prescribed without concern about it affecting your test results. However, always inform your healthcare provider about all medications you're taking when undergoing any medical tests. It is essential to consider the potential effects of other medications on PSA levels, as some may interfere with test results, but olmesartan is not known to have such an effect.

References

Research

Olmesartan.

Profiles of drug substances, excipients, and related methodology, 2017

Research

Antihypertensive effects of olmesartan compared with other angiotensin receptor blockers: a meta-analysis.

American journal of cardiovascular drugs : drugs, devices, and other interventions, 2012

Research

Is there still a role for digital rectal examination in the prostate cancer diagnostic pathway in the COVID-19 and post COVID-19 era?

The aging male : the official journal of the International Society for the Study of the Aging Male, 2021

Research

Digital rectal examination in primary care is important for early detection of prostate cancer: a retrospective cohort analysis study.

The British journal of general practice : the journal of the Royal College of General Practitioners, 2014

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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