From the Research
Inflammation of the spermatic cord typically does not elevate PSA test levels, as PSA is primarily produced by the prostate gland and conditions affecting the prostate are the main causes of elevated PSA levels. The spermatic cord is anatomically separate from the prostate gland, so inflammation in this area generally doesn't impact PSA production. However, if the inflammation is severe or spreads to involve the prostate, then PSA levels might rise.
Key Points to Consider
- PSA is produced primarily by the prostate gland, and conditions directly affecting the prostate such as prostatitis, benign prostatic hyperplasia (BPH), or prostate cancer are the main causes of elevated PSA levels 1, 2, 3.
- The relationship between digital rectal examination (DRE), transrectal ultrasonography (TRUS), and PSA levels in detecting prostate cancer has been studied, but these studies do not directly address the impact of spermatic cord inflammation on PSA levels 1, 2, 3.
- A study on the mechanism of inflammatory-associated impairment of sperm function, spermatogenesis, and steroidogenesis provides insight into the effects of inflammation on male reproductive disorders, but does not specifically address PSA levels 4.
- Age, PSA level, and DRE findings are determinants of the probability of having prostate cancer, but spermatic cord inflammation is not a factor considered in these assessments 5.
Clinical Implications
If you're experiencing spermatic cord inflammation and are concerned about PSA results, it's essential to inform your healthcare provider about your condition before PSA testing. This allows for proper interpretation of results, as they may recommend delaying the PSA test until the inflammation resolves to avoid potentially misleading results. Treatment for spermatic cord inflammation typically involves antibiotics if bacterial infection is suspected, anti-inflammatory medications, and supportive measures rather than interventions aimed at managing PSA levels.