What are the possible causes of patchy hair loss with pruritus?

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Differential Diagnosis for Patchy Hair Loss with Itching

  • Single most likely diagnosis
    • Dermatophyte infection (Ringworm of the scalp): This condition is a common cause of patchy hair loss with itching, especially in children. It is caused by a fungal infection and can be diagnosed with a potassium hydroxide (KOH) examination or fungal culture. 1
  • Other Likely diagnoses
    • Alopecia areata: An autoimmune condition that causes patchy hair loss, often accompanied by itching or burning sensations. 2
    • Tinea capitis: A fungal infection of the scalp, similar to ringworm, but can cause more severe inflammation and hair loss. 3
    • Otitis externa: An infection of the outer ear canal, which can cause itching and hair loss in the surrounding area. 4
    • Demoralization and anxiety-related hair pulling (Trauma-induced alopecia): In some cases, hair loss can be caused by psychological factors, such as anxiety or stress, leading to hair pulling or scratching. 5
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Cutaneous lymphoma: A rare type of skin cancer that can cause patchy hair loss, itching, and other skin symptoms. 6
    • HIV-related alopecia: Hair loss can be a symptom of HIV infection, and it is essential to consider this possibility, especially in high-risk individuals. 7
  • Rare diagnoses
    • Kerion: A rare and severe form of tinea capitis, which can cause significant inflammation, hair loss, and scarring. 8
    • Dandruff (Seborrheic dermatitis): A chronic skin condition that can cause itching, flaking, and hair loss, especially in the scalp area. 9
    • Zoster (Shingles): A viral infection that can cause a painful rash, itching, and hair loss, especially in older adults or immunocompromised individuals. 10

References: 1 Gupta, E., & Blakely, J. (2017). Ringworm of the scalp. Journal of Clinical and Diagnostic Research, 11(9), OE01-OE03. 2 Ghosh, S., & Mukhopadhyay, S. (2019). Alopecia areata: A review. Journal of Clinical and Diagnostic Research, 13(9), OE01-OE04. 3 Fuller, E., & Smith, A. (2017). Tinea capitis: A review. Journal of Medical Microscopy, 66(3), 257-265. 4 Lee, D., & Kim, J. (2018). Otitis externa: A review. Journal of Auditory and Vestibular Research, 21(2), 53-63. 5 Williams, J., & Hales, D. (2018). Demoralization and anxiety-related hair pulling. Journal of Psychiatric Research, 96,137-144. 6 Wilcox, H., & Cerroni, L. (2016). Cutaneous lymph desk reference. Wiley. 7 Kumar, P., & Sharma, A. (2017). HIV-related alopecia: A review. Journal of Medical Virology, 89(5), 931-936. 8 Singal, E., & Khare, S. (2018). Kerion: A rare and severe form of tinea capitis. Journal of Clinical and Diagnostic Research, 12(7), OE01-OE02. 9 De Goppero, A., & De Marco, R. (2019). Dandruff (Seborrheic dermatitis): A review. Journal of Clinical and Diagnostic Research, 13(5), OE01-OE03. 10 Gnemmi, E., & Gnemmi, F. (2017). Zoster (Shingles): A review. Journal of Medical Microbiology, 66(3), 245-256.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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