Primary Care Preventive Screening Schedule
A comprehensive primary care preventive screening schedule should include age- and sex-specific cancer screenings, cardiovascular risk assessment, metabolic screening, immunizations, and behavioral health assessments, with the specific tests and intervals determined by patient age, sex, and risk factors. 1
Cancer Screening
Breast Cancer
- Women should begin annual mammography at age 40 according to the American Cancer Society 1
- The USPSTF recommends biennial screening mammography for women aged 50 to 74 years, with individualized decision-making for women aged 40-49 years 2
- Women aged 60-69 years derive the greatest mortality benefit from screening 2
Cervical Cancer
- Begin Pap testing at age 21 or when sexually active 2
- After three consecutive normal annual Pap tests, screen every 3 years 2
- For women aged 30-65 years, Pap test with HPV DNA testing every 5 years is an acceptable alternative 2, 1
- Discontinue regular testing after age 65 if prior results have been consistently normal 2
Colorectal Cancer
- Begin screening at age 50 for average-risk adults 2, 1
- Recommended options include: 2, 1
- Annual high-sensitivity fecal occult blood test (FOBT) or fecal immunochemical test (FIT)
- Colonoscopy every 10 years
- Flexible sigmoidoscopy every 5 years
- CT colonography every 5 years
- Continue screening until at least age 75 for those with life expectancy >10 years 3
Prostate Cancer
- For men aged 55-69 years, engage in shared decision-making regarding PSA testing 1
- Begin discussions at age 50 for average-risk men with at least 10-year life expectancy 2
- Begin at age 45 for high-risk men (African-American or family history) 2
- The USPSTF and Canadian Task Force do not recommend routine screening for the general population 2
Lung Cancer
- Screen adults aged 55-80 years with annual low-dose CT if they have ≥30 pack-year smoking history and currently smoke or quit within the past 15 years 2, 4
- Screening requires access to high-volume, high-quality screening and treatment centers 2
Cardiovascular Risk Assessment
- Measure blood pressure annually in all adults 1, 3
- Screen adults aged 40-75 years for lipid panel (total cholesterol, HDL, LDL, triglycerides) 1
- Use ACC/AHA risk calculator to guide statin therapy decisions 3
Metabolic Screening
Diabetes
- Screen with fasting glucose or hemoglobin A1C in adults aged 40-75 years 1, 3
- Screen more frequently in adults with BMI ≥30 kg/m² 1
Thyroid
- Screen with TSH test, particularly in women 1
Comprehensive Metabolic Panel
- Perform CMP to assess kidney function, liver function, and electrolyte balance 1
Additional Recommended Screenings
Hematologic
- Complete Blood Count (CBC) to screen for anemia, infection, and blood disorders 1
Urinary
- Urinalysis to screen for kidney disease and urinary tract infections 1
Behavioral Health
Sexually Transmitted Infections
- Screen for syphilis, gonorrhea, and chlamydia when indicated by risk factors 1
Cognitive Function (Age ≥65)
- Screen using validated tools such as the Montreal Cognitive Assessment (MoCA) 3
Immunizations
- Annual influenza vaccination for all adults 3
- Pneumococcal vaccination as appropriate for age 3
- Tetanus-diphtheria booster every 10 years 5
Cancer-Related Checkup
- Perform cancer-related checkup every 3 years for ages 20-39, annually for age 40 and older 2
- Include health counseling on tobacco, sun exposure, diet, nutrition, and risk factors 2
- Examine thyroid, oral cavity, skin, lymph nodes, ovaries (women), and testicles (men) 2
System Factors to Improve Screening Rates
Common pitfall: Relying solely on opportunistic screening during acute care visits results in poor preventive care delivery 2
To maximize screening effectiveness: 1
- Implement reminder systems to alert patients when screenings are due
- Reduce organizational barriers to completing screening
- Promote continuity in patient information and management
- Address access barriers including insurance coverage and geographic distance
Critical consideration: A recommendation from a healthcare professional is among the strongest predictors of screening utilization 2. Regular preventive health examinations provide the best opportunity for comprehensive screening 2.