What is Gillian-Barre (Guillain-Barré) syndrome?

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Last updated: March 30, 2025View editorial policy

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From the Guidelines

I don't have specific information about a person named Gillian Barr, and without additional context, I cannot provide a meaningful answer about this individual. To give you accurate information about Gillian Barr, I would need more details such as their profession, accomplishments, or the specific context in which you're interested in learning about them. If you're looking for information about a medical condition, treatment, or other health-related topic, please provide more specific details so I can give you a helpful response. The provided evidence discusses Guillain-Barré syndrome (GBS), a rare immune-mediated disease of the peripheral nerves and nerve roots, which is usually triggered by infections 1. Some key points about GBS include:

  • It is characterized by rapidly progressive ascending weakness that initially affects the limbs and can eventually affect the cranial and respiratory muscles 1.
  • The severity of GBS is highly variable, ranging from mild distal limb weakness to complete paralysis, respiratory failure, and even death 1.
  • Diagnosis of GBS is based on the patient history and neurological, electrophysiological, and cerebrospinal fluid (CSF) examinations 1.
  • Disease progression can be rapid, and most patients with GBS reach their maximum disability within 2 weeks 1. However, without more context about Gillian Barr, I cannot provide a more specific answer. If you have any further questions or would like to know more about a specific topic related to GBS or any other medical condition, please let me know.

From the Research

Guillain-Barré Syndrome

  • Guillain-Barré Syndrome (GBS) is a rare neurological disorder that can be diagnosed and treated based on clinical criteria, cerebrospinal fluid (CSF) findings, and electrophysiological results 2
  • The diagnostic approach for GBS should be based on clinical criteria, with support from CSF and electrophysiological findings, and repetition of invasive procedures should only be done if the diagnosis cannot be ascertained from other criteria 2
  • Treatment for severe or persistently-progressive GBS includes intravenous immunoglobulin (IVIG), while plasmapheresis is recommended for cases of IVIG intolerance or inefficacy 2

Supportive Care

  • Supportive care for patients with GBS includes the use of heparin and graduated pressure stockings to prevent deep vein thrombosis, monitoring for blood pressure, pulse, autonomic disturbances, and respiratory failure, and the timely institution of artificial ventilation and tracheostomy 3
  • Pain management for GBS patients can be difficult, but carbamazepine or gabapentin may help, and the cautious use of narcotic analgesics may be needed 3
  • Disabled patients should be treated by a multidisciplinary rehabilitation team and should receive an assistive exercise program, and persistent fatigue following GBS may be helped by an exercise program 3

Complete Blood Count (CBC)

  • CBC is a common blood test that evaluates the total numbers and characteristics of cell components in the blood, and can be used to predict the risk of cancer, cardiovascular disease, arteriosclerosis, type 2 diabetes, and metabolic syndrome 4
  • CBC components such as white blood cell count, neutrophil-to-lymphocyte ratio, hemoglobin, mean corpuscular volume, red cell distribution width, platelet count, mean platelet volume, and platelet-to-lymphocyte ratio can be used as markers to predict cardiovascular and metabolic diseases 4
  • Waist circumference is highly correlated to CBC constituents, and obese patients may have different "normal values" for CBC parameters 5

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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