What are the grades of cryotherapy burns?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: November 14, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Cryotherapy Burns: Classification and Grading

The provided evidence does not contain a formal grading system specifically for cryotherapy burns. However, based on the available literature, cryotherapy-related skin injuries can be understood through the lens of thermal burn classification and specific complications documented in the literature.

Understanding Cryotherapy-Related Skin Injuries

Cryotherapy can cause skin damage ranging from superficial irritation to full-thickness burns, but these are classified using standard thermal burn depth categories rather than a cryotherapy-specific grading system. 1, 2, 3

Classification by Burn Depth

Cryotherapy-induced skin injuries follow the same depth classification as thermal burns:

  • Superficial burns: Affect only the epidermis, similar to first-degree burns 4
  • Partial-thickness burns: Extend into the dermis, equivalent to second-degree burns 2
  • Full-thickness burns: Involve complete destruction of skin layers, analogous to third-degree burns 4

Documented Complications from Cryotherapy

The literature describes several specific injury patterns from cryotherapy rather than formal "grades":

  • Skin irritation: The mildest form of injury, commonly reported 5
  • Frostbite: Tissue freezing injury from excessive cold exposure 1, 3
  • Perniosis: Inflammatory skin condition from cold exposure 5
  • Peripheral nerve injuries: From prolonged or excessive cold application 5, 3
  • Partial-thickness skin burns: Documented in pediatric cases following inappropriate cryotherapy use 2

Clinical Context and Prevention

The severity of cryotherapy burns depends on duration of application, temperature achieved, and patient-specific factors. 3

Key Risk Factors

  • Direct ice application to skin can cause tissue ischemia 1
  • Prolonged application increases injury risk 5
  • Pediatric patients are at higher risk, particularly when cryotherapy is applied to misdiagnosed injuries (such as fractures mistaken for soft tissue injuries) 2
  • Patients with diabetes mellitus, multiple sclerosis, poor circulation, and spinal cord injuries have increased susceptibility to cold-induced burns 3

Prevention Strategies

  • Avoid direct ice application; use barriers between ice and skin 1
  • Limit application duration (typically 10-20 minutes for acute injuries) 1
  • Monitor skin appearance during treatment 5
  • Ensure proper diagnosis before applying cryotherapy, especially in children where fractures are more common than ligamentous injuries 2
  • Patient education is essential to avoid complications 5

Important Clinical Caveat

In the context of medical cryotherapy for prostate cancer treatment, the term "cryotherapy" refers to a completely different procedure involving deliberate tissue destruction at -40°C, with complications including erectile dysfunction, urinary incontinence, and fistula formation—this should not be confused with superficial cryotherapy for musculoskeletal injuries. 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Skin burns following cryotherapy in misdiagnosed pediatric injuries.

Journal of bodywork and movement therapies, 2018

Guideline

Burn Management Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.