Can epicatechin 500mg supplementation drastically lower zinc levels?

Given the potential for interaction and the importance of maintaining adequate zinc levels, it is recommended to exercise caution when supplementing with epicatechin, especially at doses of 500mg. While direct evidence may be limited, it is prudent to assume that high doses of epicatechin could potentially lower zinc levels drastically, especially in individuals with marginal zinc status or those not consuming enough zinc through their diet. To mitigate this risk, it is advisable to ensure adequate zinc intake through diet or supplementation. A daily zinc supplement of 15-20 mg, taken at a different time of day from the epicatechin, could help maintain zinc levels. Additionally, monitoring zinc levels and adjusting the supplement regimen as needed under medical supervision is recommended. If zinc levels do become depleted, increasing the zinc supplement dose to 30-50 mg daily for a short period, under close medical supervision, may be necessary to replenish stores. It is also important to consider the overall dietary pattern and ensure it includes zinc-rich foods to support zinc status.