What is the possible diagnosis for a 13-year-old female presenting with a mild itchy rash, characterized by small, round, flat, darker skin-colored lesions on the chest, neck, and back of the neck, which started 3 days ago and worsens at night, while using Selsun Blue (selenium sulfide) shampoo?

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Possible Diagnosis: Pityriasis Versicolor (Tinea Versicolor)

The most likely diagnosis is pityriasis versicolor (tinea versicolor), a superficial fungal infection caused by Malassezia furfur, which characteristically presents as hyperpigmented or hypopigmented flat, round patches on the trunk and neck that worsen with itching at night. 1

Clinical Features Supporting This Diagnosis

  • The description of small, round, flat lesions with darker pigmentation on a Black patient's chest and neck is classic for pityriasis versicolor, which commonly presents as hyperpigmented patches in darker-skinned individuals 1

  • The distribution pattern (chest, neck, back of neck) is typical for tinea versicolor, as this fungal infection predominantly affects the trunk and proximal extremities 1, 2

  • Mild pruritus that worsens at night is consistent with this diagnosis, though itching is typically mild to moderate in pityriasis versicolor 1

  • The 3-day timeline suggests an acute awareness of a chronic condition rather than a new infection, as tinea versicolor is often present for weeks before patients notice it 1

Why Selsun Blue Was Mentioned

  • The patient's use of Selsun Blue (selenium sulfide) is actually appropriate, as selenium sulfide 1-2.5% is a traditional and effective treatment for pityriasis versicolor 1, 2, 3

  • However, selenium sulfide requires proper application technique: it should be applied to the entire affected area for 5-15 minutes daily for 18 days, not just used as a regular shampoo 3

  • The patient may have been attempting self-treatment, which suggests they or a family member suspected a fungal condition 2

Diagnostic Confirmation Needed

  • Direct microscopic examination with KOH preparation showing "spaghetti and meatballs" appearance (hyphae and spores) confirms the diagnosis 2, 4

  • Wood's lamp examination may show yellow-gold fluorescence, though this is not always present 3

  • Clinical diagnosis alone is often sufficient when the characteristic appearance and distribution are present 1, 2

Alternative Diagnoses to Consider (Less Likely)

  • Post-inflammatory hyperpigmentation could present similarly but would require a preceding inflammatory condition and wouldn't typically itch 5, 6

  • Atopic dermatitis is unlikely given the flat (not raised) nature of lesions, lack of flexural involvement, and absence of dry skin or family history of atopy 5, 6

  • Secondary bacterial infection is not suggested by the absence of crusting, weeping, or erosions 7, 6

Treatment Recommendations

  • Continue selenium sulfide 2.5% (Selsun Blue), but apply correctly: lather on affected areas and leave for 10-15 minutes before rinsing, once daily for 2-3 weeks 2, 3, 8

  • Alternatively, ketoconazole 2% shampoo once weekly for 3 weeks has a 95% cure rate and may be more convenient 2

  • Treat the entire trunk and proximal extremities, not just visible lesions, as subclinical infection is common 1, 3

  • Warn the patient that pigmentation changes may persist for months after successful fungal eradication, which is normal 1

Important Caveats

  • Recurrence is extremely common (up to 60-80% of patients) even after successful treatment, so prophylactic monthly applications may be needed 1, 2

  • The darker pigmentation will not resolve immediately with antifungal treatment—it may take 6-12 months for skin color to normalize 1

  • If no improvement after 3-4 weeks of proper treatment, consider alternative diagnoses or refer to dermatology 2, 4

References

Research

Diagnosis and treatment of tinea versicolor.

The Journal of family practice, 1996

Research

Comparative study of ketoconazole versus selenium sulphide shampoo in pityriasis versicolor.

Indian journal of dermatology, venereology and leprology, 2003

Guideline

Management of Eczema in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Diagnostic Approach to Skin Eruptions in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Eczema Herpeticum in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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