Lower Uterine Segment Scar Thickness After Previous Cesarean Section
A lower uterine segment scar thickness of ≥3.5 mm measured by ultrasound in the third trimester is considered normal and safe for trial of labor, while measurements <3.5 mm indicate increased risk of scar dehiscence and warrant elective repeat cesarean section. 1, 2
Normal Scar Thickness Parameters
Third trimester measurements (≥36 weeks):
- Mean thickness in women who successfully deliver vaginally: 3.3 ± 0.7 mm 3
- Mean thickness in women requiring repeat cesarean: 2.9 ± 0.9 mm 3
- The critical threshold ("cut-off value") is 3.5 mm - below this indicates significantly elevated risk 1, 2
Late second trimester measurements (24-28 weeks):
- Mean thickness in women who deliver vaginally: 4.8 ± 1.1 mm 3
- Mean thickness in women requiring cesarean: 4.4 ± 1.1 mm 3
- Scars thin progressively during pregnancy, with mean decrease of approximately 1.7-1.9 mm from second to third trimester 3
At-Risk Scar Thickness Definitions
Pathological thinning occurs when the uterine wall measures only a few millimeters thick and is composed entirely of fibrotic scar tissue - this represents uterine scar dehiscence (USD). 4
Critical risk thresholds:
- <2.3 mm: High sensitivity marker for uterine scar dehiscence, detecting 85-90% of cases when using transvaginal ultrasound or combined approach 5
- <3.5 mm: Established threshold below which trial of labor carries significantly increased risk; 56.6% of women with measurements below this require elective cesarean 2
Optimal Measurement Technique
Combined transabdominal and transvaginal ultrasound approach provides superior accuracy:
- Transvaginal ultrasound alone: 85% area under curve for detecting dehiscence 5
- Combined measurement (using the thinner of the two): 88% area under curve 5
- Transabdominal alone: only 78% area under curve 5
The thinnest portion measured at multiple sites (3-4 locations) of the lower uterine segment should be considered the true scar thickness. 3
3D ultrasound demonstrates superior diagnostic accuracy compared to 2D ultrasound, with statistically significant differences in specificity (0.04), sensitivity (0.05), positive predictive value (0.01), and negative predictive value (0.01). 1
Clinical Assessment Integration
Scar tenderness on physical examination remains highly valuable:
- Sensitivity: 46.2% for detecting thinned-out scars 6
- Specificity: 97.1% 6
- Positive predictive value: 92.3% 6
- When scar tenderness is present, 92.3% of cases will have intraoperative scar thinning 6
Ultrasound measurement alone has limitations:
- Sensitivity for predicting thinned-out scar: only 19.2% 6
- Specificity: 94.1% 6
- Clinical examination showing scar tenderness correlates significantly with intraoperative findings (κ = 0.46; p<0.05), while ultrasound correlation is not statistically significant 6
Timing of Measurement
Third trimester measurement (≥36 weeks) has better correlation with mode of delivery than second trimester measurement and should be the primary decision-making timepoint. 3
Measurements at 38-40 weeks gestation provide the most clinically relevant assessment for determining delivery mode. 1
Common Pitfalls to Avoid
Using transabdominal ultrasound alone - this systematically overestimates scar thickness (mean 3.8 mm) compared to transvaginal (3.5 mm) or combined approach (3.2 mm), potentially missing 55% of dehiscence cases 5
Relying solely on ultrasound without clinical correlation - scar tenderness has higher positive predictive value (92.3%) than ultrasound thickness measurement alone (71.4%) 6
Measuring only one location - the scar must be assessed at 3-4 sites with the thinnest measurement used for risk stratification 3
Ignoring the progressive thinning during pregnancy - scars decrease approximately 1.5-2.0 mm from mid-pregnancy to term, so early measurements cannot substitute for third trimester assessment 3
Risk-Based Management Algorithm
For scar thickness ≥3.5 mm in third trimester:
- Trial of labor is reasonable if no other contraindications exist 2
- Women with thicker scars have significantly better chances of successful vaginal birth after cesarean 3
For scar thickness 2.3-3.5 mm:
- Increased vigilance required during labor 5
- Consider elective repeat cesarean, particularly if additional risk factors present (no prior vaginal delivery, need for induction, unfavorable cervix) 2
For scar thickness <2.3 mm:
- Elective repeat cesarean section strongly recommended 5
- This threshold detects 85-90% of uterine scar dehiscence cases 5
- Risk of uterine rupture increases substantially below this measurement 5
When scar tenderness is present on examination:
- Proceed directly to elective cesarean section regardless of ultrasound measurement - 92.3% positive predictive value for intraoperative scar thinning 6