What is the ICD 10 (International Classification of Diseases, 10th Revision) code for a postoperative wound infection?

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Last updated: November 16, 2025View editorial policy

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ICD-10 Code for Postoperative Wound Infection

The ICD-10 code for postoperative wound infection is T81.4 (Infection following a procedure). 1

Primary Coding

  • Use T81.4 as the primary code when clinical signs of surgical site infection are present, including erythema and purulent or serous drainage from the wound 1
  • This code applies to infections occurring within 30 days after surgery involving the skin, subcutaneous tissue, or deeper tissues 2

Clinical Documentation Requirements for Accurate Coding

To support proper coding with T81.4, your clinical documentation should include: 1

  • Presence and extent of erythema (with measurements)
  • Character of drainage (purulent, serous, or serosanguineous)
  • Associated local signs (warmth, tenderness, induration)
  • Systemic signs (fever, elevated white blood cell count)
  • Gram stain and culture results when obtained

Timing Considerations

  • Infections appearing after 96 hours postoperatively are more likely to represent true infection and warrant the T81.4 code 1
  • Fever and wound changes in the first 48-72 hours typically represent non-infectious inflammatory responses rather than true infection 1
  • The rare exceptions are group A streptococcal or clostridial infections, which can occur within the first 48 hours 1

Additional Coding Considerations

When applicable, consider adding: 1

  • Organism-specific codes if MRSA is suspected or confirmed
  • Polymicrobial infection codes for wounds of the perineum or operations involving the GI tract or female genital tract
  • Separate procedure codes for suture removal plus incision and drainage when performed

Common Pitfalls to Avoid

  • Do not code early postoperative inflammation (first 48-72 hours) as infection unless there is clear evidence of group A streptococcal or clostridial infection 1
  • The wound classification (clean, clean-contaminated, contaminated, dirty) should be reflected in your clinical documentation to support the infection diagnosis 1
  • The positive predictive value of T81.4 coding is approximately 35%, so ensure clinical documentation clearly supports the diagnosis 3

References

Guideline

ICD-10 Coding for Surgical Wound Infections

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Surgical Site Infections: Definition, Epidemiology, and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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