What is the diagnosis for a 4-12 year old female with severe abdominal pain, nausea, vomiting, and an episode of diarrhea with mucus?

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Diagnosis: Intussusception

The diagnosis is intussusception, as severe abdominal pain, nausea, vomiting, and diarrhea with mucus in a 4-12 year old female are characteristic of this condition, where one bowel segment telescopes into another. 1

Clinical Reasoning

The presentation of severe abdominal pain combined with mucoid diarrhea is the key distinguishing feature here. The presence of mucus in the stool represents an early stage of intussusception, occurring before progression to the classic "currant jelly" bloody stools that develop as bowel ischemia advances 1. This clinical picture differs significantly from simple viral gastroenteritis, which typically presents with milder symptoms, fever, and watery diarrhea without mucus 1.

Age-Specific Considerations

While intussusception classically affects infants between 5-9 months of age 2, it remains an important diagnosis in the 4-12 year age range 1. In this older pediatric population, the severity of pain and presence of mucus in stool are crucial differentiating factors from more common conditions like gastroenteritis or constipation 1.

Important Clinical Caveat

The classic triad of abdominal pain, bloody stools, and palpable abdominal mass is actually seen in only a minority of patients 3. More commonly, children present with nonspecific findings including lethargy, irritability, vomiting, and the mucoid stools described in this case 3, 2. This makes early diagnosis dependent on maintaining a high index of suspicion 3.

Immediate Diagnostic Approach

  • Ultrasound should be performed early as it is safe, sensitive, and specific for diagnosing intussusception 3
  • Plain abdominal radiography lacks sufficient sensitivity to reliably exclude intussusception, though it may be part of the initial workup 3
  • Contrast enema (pneumatic or hydrostatic) serves as both the gold standard for diagnosis and first-line treatment 3

Critical Pre-Treatment Steps

Before attempting contrast enema reduction 3:

  • Establish intravenous access
  • Initiate fluid resuscitation
  • Notify the pediatric surgeon

This is a surgical emergency requiring immediate evaluation and intervention to prevent bowel ischemia, perforation, and peritonitis 4, 2.

References

Guideline

Diagnosis and Management of Intussusception

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Intussusception.

American family physician, 1996

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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