Restarting Wegovy After Missing 2 Weeks
No, you should not advance to 1.7 mg after missing 2 weeks at the 1 mg dose—resume at your previous 1 mg dose instead. 1
Guideline-Based Recommendation for Missed Doses
After missing 1-2 doses of semaglutide that were previously well-tolerated, you can resume at the same dose without restarting the titration schedule. 1 This applies directly to your situation where you missed 2 weeks (2 doses) while on 1 mg.
When to Restart Titration
- If you had missed 3 or more consecutive doses, you would need to consider restarting the entire titration schedule from a lower dose 1, 2
- The rationale is that missing multiple doses increases the risk of gastrointestinal side effects when resuming at higher doses 1
Why Not Jump to 1.7 mg
Advancing to a higher dose after a treatment interruption significantly increases your risk of gastrointestinal adverse events (nausea, vomiting, diarrhea), which are dose-dependent with semaglutide. 1, 3
Key Safety Considerations
- Slow dose titration is specifically designed to minimize gastrointestinal side effects 1
- Gastrointestinal adverse events are the most common reason patients discontinue semaglutide treatment (4.5% discontinuation rate in clinical trials) 3
- These side effects are typically transient and mild-to-moderate when proper titration is followed 3
Practical Next Steps
Resume your 1 mg weekly injections immediately:
- Take your next dose as soon as possible 1
- Continue at 1 mg for the standard duration before considering advancement to 1.7 mg 1
- Do not try to "make up" for missed doses 2
Impact on Treatment Goals
- Missing 2 weeks may temporarily impact your glycemic control and weight management benefits 1
- However, resuming at your established dose maintains continuity without unnecessary risk 1
- Regular adherence going forward is essential for optimal therapeutic effects 1
The conservative approach of resuming at 1 mg protects you from preventable side effects while maintaining your treatment progress.