Association Between Parity and Abnormal Uterine Bleeding
The provided evidence does not contain any research demonstrating an association between increased parity and abnormal uterine bleeding (AUB).
Analysis of Available Evidence
After reviewing all provided studies, none specifically examined or reported on the relationship between parity (number of pregnancies carried to viable gestational age) and the development of AUB. The evidence focuses on:
Classification systems: The PALM-COEIN classification system categorizes AUB causes into structural (polyp, adenomyosis, leiomyoma, malignancy) and nonstructural (coagulopathy, ovulatory dysfunction, endometrial disorders, iatrogenic) etiologies, but does not identify parity as a risk factor 1, 2, 3.
Common causes identified: The most frequently documented causes of AUB in the provided evidence include ovulatory dysfunction (31.6% of cases), leiomyomas (16.8%), adenomyosis, and endometrial polyps 3, 4.
Risk factors discussed: The available research identifies age, BMI (with overweight/obesity affecting 64.2% of AUB patients), and specific structural abnormalities as significant predictors of AUB, but parity is not mentioned as a contributing factor 3.
Clinical Implication
Without specific research evidence linking parity to AUB in the provided literature, any association between these factors cannot be confirmed or refuted based on this evidence set. The systematic evaluation of AUB should focus on the established PALM-COEIN classification rather than parity as a primary consideration 1, 2.
The absence of parity as a documented risk factor in recent comprehensive reviews of AUB management suggests it is not considered a major contributor to this condition in current clinical practice 5, 1, 2, 3, 4.