What is the most likely cause of sudden onset abdominal pain and diarrhea 1 hour after eating rojak, in two individuals who ate at the same location?

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Staphylococcus aureus Food Poisoning

The most likely aetiology is d) Staphylococcus aureus, given the extremely rapid onset of symptoms (1 hour after eating) and the common-source outbreak pattern affecting multiple individuals who shared the same meal. 1

Key Diagnostic Features Supporting Staph aureus

The clinical presentation is pathognomonic for bacterial toxin-mediated food poisoning:

  • Incubation period of 1 hour is characteristic of preformed bacterial toxins, specifically from Staphylococcus aureus, Bacillus cereus, or Clostridium perfringens, which cause symptoms within 1-72 hours of ingestion 1

  • Abrupt onset of nausea, vomiting, and abdominal cramps within 1-4 hours after eating contaminated food is the hallmark presentation of enterotoxin-producing foodborne strains, particularly S. aureus 1, 2

  • Common-source outbreak pattern (both individuals who ate together developed identical symptoms) strongly indicates a foodborne toxin rather than person-to-person transmission 1

  • Absence of fever and inflammatory signs is expected with preformed toxin-mediated illness, distinguishing it from invasive bacterial pathogens 1

Why Other Options Are Less Likely

Enterotoxigenic E. coli (ETEC)

  • ETEC typically has an incubation period of 12-72 hours, far too long for this 1-hour presentation 1
  • Predominantly causes watery diarrhea rather than the vomiting-predominant picture seen here 1

Shigella and Salmonella

  • Both require 12-48 hours incubation period for symptoms to develop 1
  • These invasive pathogens typically cause fever, bloody stools, and systemic symptoms 1
  • The 1-hour timeframe is incompatible with these organisms 1

Vibrio cholerae

  • Incubation period is 24-48 hours 1
  • Presents with profuse "rice water" diarrhea rather than vomiting and abdominal pain 1
  • Requires exposure to brackish water or undercooked shellfish, not typical street food 1

Expected Clinical Course

  • Symptoms resolve within 24-48 hours with supportive care alone, which is characteristic of toxin-mediated food poisoning 1

  • Diarrhea may develop 5-10 hours after the initial vomiting, but the illness remains self-limited 2

  • No antibiotic therapy is indicated as this is toxin-mediated rather than an active infection requiring antimicrobial treatment 1

Critical Clinical Pitfall

Do not confuse this presentation with viral gastroenteritis or invasive bacterial infection requiring antibiotics. The extremely rapid onset (1 hour) and common-source pattern are diagnostic of preformed bacterial toxin, specifically S. aureus in this context. 1, 2 Viral gastroenteritis would have a longer incubation period (typically 24-48 hours) and would last several days rather than resolving within 24-48 hours. 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Food Poisoning Symptom Onset and Duration

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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