What is the medical term for an infected wound?

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Medical Terminology for Infected Wounds

The medical term for an infected wound depends on the anatomical location and depth: "surgical site infection" (SSI) for postoperative wounds, "wound infection" for general traumatic or chronic wounds, and "diabetic foot infection" (DFI) for infected foot wounds in diabetic patients. 1, 2

Primary Terminology by Context

Surgical Wounds

  • Surgical Site Infection (SSI) is the formal medical term for infected surgical wounds, defined as infections occurring within 30 days after surgery (or up to 1 year if prosthetic material was implanted) 1, 2
  • SSIs are further classified into three anatomical categories: superficial incisional (involving skin and subcutaneous tissue), deep incisional (involving fascia and muscle), and organ/space infections (involving organs or spaces distinct from the incision) 1

Diabetic Foot Wounds

  • Diabetic Foot Infection (DFI) is the specific term for infected wounds below the malleoli in patients with diabetes 2
  • DFI is defined clinically by the presence of ≥2 classic signs of inflammation: local swelling/induration, erythema, tenderness/pain, warmth, or purulent discharge 2

General Wound Terminology

  • Wound infection is the general term used for any wound where microorganisms invade and multiply in host tissues, inducing an inflammatory response and tissue damage 3, 4
  • This distinguishes from wound colonization, where bacteria are present on the wound surface without tissue invasion or inflammatory response 2

Diagnostic Criteria

Clinical Signs (Classic Inflammatory Markers)

  • The traditional signs are: dolor (pain), rubor (redness), calor (warmth), tumor (swelling), and functio laesa (loss of function) 5
  • Purulent drainage is diagnostic of infection without requiring culture confirmation 2, 1
  • Spreading cellulitis (erythema extending >0.5 cm from wound margins) indicates infection 2

Important Caveats

  • Patients with peripheral neuropathy may not exhibit pain or tenderness, and those with peripheral arterial disease may have diminished erythema and warmth, making clinical diagnosis more challenging 2
  • Not all wounds with bacteria are infected—colonization is universal in open wounds and does not require treatment 2

Microbiological Confirmation

When Culture is Diagnostic

  • Growth of >10⁵ bacteria per gram of tissue from deep tissue biopsy is diagnostic of wound infection 2
  • Organisms cultured from aseptically collected deep fluid or tissue samples confirm infection 2
  • β-hemolytic streptococci are considered pathogenic at any concentration 2

Limitations of Wound Swabs

  • Superficial wound swabs have limited diagnostic value due to inevitable contamination in open wounds 2
  • Wound swabs should only be obtained when purulence or spreading cellulitis is present 2

References

Guideline

Surgical Site Infections: Definition, Epidemiology, and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

An overview of the prevention and management of wound infection.

Nursing standard (Royal College of Nursing (Great Britain) : 1987), 2022

Research

[The infected wound].

Der Orthopade, 1988

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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