Differential Diagnosis for a CA125 of 130
Single Most Likely Diagnosis
- Ovarian Cancer: Elevated CA125 levels are commonly associated with ovarian cancer, particularly in postmenopausal women. A level of 130 is significantly higher than the normal range, making ovarian cancer a strong consideration.
Other Likely Diagnoses
- Endometriosis: This condition can cause elevated CA125 levels, especially during menstruation. However, levels are typically not as high as 130.
- Pelvic Inflammatory Disease (PID): PID can cause inflammation in the pelvic region, leading to elevated CA125 levels.
- Uterine Fibroids: Large fibroids can cause elevated CA125 levels, although this is less common.
Do Not Miss Diagnoses
- Tuberculosis: Although less common, tuberculosis can cause elevated CA125 levels and is a critical diagnosis not to miss due to its potential for severe consequences if left untreated.
- Lymphoma: Certain types of lymphoma can cause elevated CA125 levels, and missing this diagnosis could have significant implications for treatment and prognosis.
Rare Diagnoses
- Meigs' Syndrome: A rare condition characterized by a benign ovarian tumor, ascites, and pleural effusion, which can cause elevated CA125 levels.
- Sclerosing Peritonitis: A rare condition that can cause elevated CA125 levels, often associated with peritoneal inflammation and scarring.