Differential Diagnosis
- Single most likely diagnosis
- Mitral Valve Prolapse (MVP) syndrome: The presence of myxomatous leaflets and bileaflet prolapse with mild to moderate mitral regurgitation is consistent with MVP syndrome. The patient's age and the absence of other significant cardiac abnormalities also support this diagnosis.
- Other Likely diagnoses
- Barlow's disease: This condition is characterized by myxomatous degeneration of the mitral valve leaflets, which is consistent with the patient's findings. However, Barlow's disease typically involves more severe mitral regurgitation and leaflet thickening.
- Mitral regurgitation due to other causes (e.g., rheumatic heart disease, infective endocarditis): Although less likely, other conditions could cause mitral regurgitation. However, the patient's age, lack of other symptoms, and normal left atrial size make these diagnoses less probable.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Marfan syndrome: Although the patient's presentation does not strongly suggest Marfan syndrome, it is essential to consider this diagnosis due to its potential for severe cardiac and systemic complications. The presence of myxomatous mitral valve leaflets and aortic root dilatation (not mentioned in the provided information) could be indicative of Marfan syndrome.
- Arrhythmogenic right ventricular cardiomyopathy (ARVC): Although the right ventricular function is normal, it is crucial to consider ARVC due to its potential for life-threatening arrhythmias. However, the patient's age, lack of symptoms, and normal right ventricular function make this diagnosis less likely.
- Rare diagnoses
- Ebstein's anomaly: This congenital heart defect involves abnormalities of the tricuspid valve and right ventricle. Although the patient's tricuspid valve leaflets are myxomatous, the absence of other characteristic features (e.g., right ventricular dysplasia, atrial septal defect) makes this diagnosis unlikely.
- Cardiac sarcoidosis: This condition can cause mitral regurgitation due to granulomatous infiltration of the myocardium. However, the patient's age, lack of symptoms, and normal cardiac function make this diagnosis highly unlikely.