What is the safety and efficacy of Pygeum africanum bark powder for Benign Prostatic Hyperplasia (BPH)?

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From the Research

Pygeum africanum bark extract is a moderately effective and generally safe treatment option for benign prostatic hyperplasia (BPH) symptoms, with a recommended dosage of 100-200 mg daily of standardized extract (containing 13% total sterols), taken in divided doses with meals. The evidence from studies, including a Cochrane review 1, suggests that Pygeum africanum can improve urinary symptoms, including increased urinary flow rate, reduced nighttime urination, and decreased residual urine volume after 1-3 months of use. The mechanism of action likely involves anti-inflammatory effects, reduction of prostate growth factors, and inhibition of 5-alpha-reductase activity. Side effects are generally mild and may include gastrointestinal discomfort, headache, or dizziness.

Some key points to consider when using Pygeum africanum for BPH symptoms include:

  • The quality of pygeum supplements varies considerably between manufacturers, so choosing products from reputable companies with standardized extracts is important.
  • Patients should consult their healthcare provider before starting pygeum, especially if taking other medications, and should not delay seeking medical attention for urinary symptoms, as BPH requires proper diagnosis and monitoring.
  • While pygeum shows promise, its effects are modest compared to prescription medications like alpha-blockers or 5-alpha-reductase inhibitors.
  • Studies have shown that Pygeum africanum can be used in combination with other treatments, such as alpha-blockers and 5-alpha-reductase inhibitors, to improve symptoms and flowmetric indices 2.
  • The efficacy and safety of Pygeum africanum have been demonstrated in several clinical trials, including a study that compared the effectiveness of Pygeum africanum to placebo and found that Pygeum africanum provided a moderately large improvement in the combined outcome of urologic symptoms and flow measures 1.

Overall, Pygeum africanum bark extract is a viable treatment option for BPH symptoms, and its use should be considered in conjunction with other treatments and under the guidance of a healthcare provider.

References

Research

Pygeum africanum for benign prostatic hyperplasia.

The Cochrane database of systematic reviews, 2002

Research

Nutraceutical treatment and prevention of benign prostatic hyperplasia and prostate cancer.

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2019

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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