What is the first-line treatment for a first-degree burn?

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Last updated: November 18, 2025View editorial policy

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First-Line Treatment for First-Degree Burns

Immediately cool the burn with clean running water (15-25°C) for 5-20 minutes, then apply petrolatum or petrolatum-based antibiotic ointment and cover with a clean, non-adherent dressing. 1, 2

Immediate Cooling (First Priority)

The most critical first-line intervention is prompt cooling to limit tissue damage and reduce pain:

  • Apply clean running water at 15-25°C for 5-20 minutes as soon as possible after injury 3, 1, 2
  • Cooling is effective up to 3 hours post-injury and reduces pain, edema, depth of injury, and speeds healing 3, 4
  • If running water is unavailable, ice wrapped in cloth may be used for superficial burns with intact skin 2
  • Remove jewelry immediately before swelling occurs to prevent constriction and vascular compromise 1, 2

Critical Cooling Precautions:

  • Never apply ice directly to the burn as this causes tissue ischemia and further damage 3, 1
  • Monitor children closely for hypothermia during cooling, especially with larger burns 1, 2

Post-Cooling Topical Treatment

After adequate cooling, the next step is topical therapy:

  • Apply petrolatum, petrolatum-based antibiotic ointment, honey, or aloe vera to the cooled burn 1, 2
  • Aqueous emulsions with small amounts of lipids (O/W emulsions) are ideal as water evaporates to provide cooling while lipids repair the damaged skin barrier 5
  • Foam sprays and lotions are particularly well-suited because they are easy and painless to apply 5

Dressing Application

  • Cover loosely with a clean, non-adherent dressing after applying topical treatment 1, 2
  • The dressing protects the wound while allowing it to heal 1

Pain Management

  • Administer over-the-counter acetaminophen or NSAIDs for pain control 1, 2
  • These are sufficient for first-degree burns which only involve the epidermal layer 6

What NOT to Do (Common Pitfalls)

  • Do not apply butter, oil, or other home remedies as these can worsen injury 1
  • Do not use topical corticosteroids as superiority to vehicle has not been demonstrated 5
  • Do not break blisters if any form, as this increases infection risk 1
  • Do not use prophylactic antibiotics - these are not indicated and may increase bacterial resistance 4, 6

When to Seek Medical Attention

First-degree burns generally heal without scarring and have low infection risk 2, but seek immediate care for:

  • Burns involving the face, hands, feet, or genitals 1, 2
  • Burns covering >10% body surface area in adults or >5% in children 1, 2
  • Signs of inhalation injury (soot around nose/mouth, difficulty breathing, singed nasal hairs) 2
  • Burns showing signs of infection or that are very painful 1

References

Guideline

Burn Care Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment for First Degree Burns

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Minor burn management: potions and lotions.

Australian prescriber, 2015

Research

[Rational treatment of first-degree burns].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2007

Research

Outpatient Burn Care: Prevention and Treatment.

American family physician, 2020

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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