What is the evidence for chiropractic care in treating back pain?

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Last updated: November 18, 2025View editorial policy

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Evidence for Chiropractic Care in Back Pain

Chiropractic spinal manipulation is a moderately effective treatment option for both acute and chronic low back pain, with small to moderate short-term benefits for acute cases and moderate benefits for chronic cases, comparable to other effective therapies like exercise and physical therapy. 1

Acute Low Back Pain (< 4 weeks)

For acute low back pain, spinal manipulation provides small to moderate short-term benefits and should be considered when patients do not improve with self-care options. 1

  • Spinal manipulation administered by appropriately trained providers shows superiority over sham manipulation, with pain reduction of approximately 10 points on a 100-point visual analogue scale 1
  • Functional improvement on the Roland-Morris Disability Questionnaire (RDQ) averages 2.8 points, though this did not reach statistical significance 1
  • No clear differences exist between spinal manipulation and usual care, analgesics, physical therapy, or exercise therapy for acute cases 1
  • The evidence quality is moderate, with a weak recommendation strength from the American College of Physicians and American Pain Society 1

Chronic Low Back Pain (> 3 months)

For chronic low back pain, spinal manipulation demonstrates moderate effectiveness and is one of several evidence-based nonpharmacologic treatment options. 1

  • Against sham manipulation, pain reduction averages 10 points short-term and 19 points long-term on a 100-point scale 1
  • Functional improvement averages 3.3 points on the RDQ in the short term 1
  • A large trial (1,334 patients) found spinal manipulation slightly superior to usual care for pain and disability (approximately 5 points on 100-point scales) at 3 months, though effects diminished by 12 months 1
  • Chiropractic care appears relatively cost-effective for chronic low back pain compared to medical care 2
  • Patients with chronic low back pain in chiropractic settings achieved average 52.5% pain reduction and 52.9% disability reduction 3

Subacute Low Back Pain (4-8 weeks)

For subacute low back pain, spinal manipulation can be considered, though evidence is limited as most trials enrolled mixed populations of chronic and subacute patients. 1

  • Results from chronic low back pain studies may reasonably be applied to subacute cases 1
  • One trial found manipulation slightly superior to usual care with approximately 5-point improvement on 100-point scales at 3 months 1

Comparative Effectiveness

Spinal manipulation performs comparably to other effective treatments, with no single therapy established as superior first-line treatment. 1

  • No significant differences exist between manipulation and general practitioner care, analgesics, physical therapy, exercises, or back schools 1
  • One trial (681 patients) found no differences between chiropractic care and medical management for pain, functional status, or other outcomes 1
  • Adding manipulation to exercise therapy provides no additional benefit over exercise alone 1
  • Evidence is insufficient to determine whether benefits vary by profession of the manipulator (chiropractor vs. other trained clinician) 1

Treatment Intensity

For chronic low back pain, more frequent chiropractic visits (3-4 times per week for 3 weeks) produce greater pain and disability reduction at 4 weeks. 4

  • A dose-response relationship exists, with approximately 5.7 points pain reduction per 3 additional visits 4
  • Functional disability improved by approximately 5 points per 3 additional visits 4
  • Patients in clinical practice typically receive an average of 12 treatments over a 4-week period 3

Safety Profile

Serious adverse events from spinal manipulation are extremely rare, with risk estimated at less than 1 per 1 million patient visits. 1

  • No serious complications were reported in more than 70 controlled clinical trials 1
  • Serious adverse events (such as worsening lumbar disc herniation or cauda equina syndrome) are very rare 1
  • Five systematic reviews consistently confirmed the safety profile 1

Clinical Considerations

Patient expectations of benefit should be considered when choosing spinal manipulation, as expectations influence outcomes. 1

  • Evidence is insufficient to conclude whether effectiveness varies with presence or absence of radiating pain 1
  • Few trials have evaluated effectiveness specifically in patients with radicular pain or spinal stenosis 1
  • Chiropractic patients with neck pain and concomitant headaches have higher disability scores but still achieve significant improvement 3
  • Acute/subacute patients achieve greater pain and disability reduction (66.8% and 62.5%) compared to chronic patients (19.7% and 19.8%) 3

Mechanisms of Action

Spinal manipulation inhibits back pain partly through spinal segmental mechanisms and potentially through peripheral mechanisms regulating inflammatory responses. 5

  • Spinal cord mechanisms of pain inhibition contribute to pain-relieving effects 5
  • Evidence is weaker regarding peripheral and supraspinal mechanisms 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Cost-effectiveness of medical and chiropractic care for acute and chronic low back pain.

Journal of manipulative and physiological therapeutics, 2005

Research

Dose-response for chiropractic care of chronic low back pain.

The spine journal : official journal of the North American Spine Society, 2004

Research

Neurophysiological mechanisms of chiropractic spinal manipulation for spine pain.

European journal of pain (London, England), 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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