Management of Moderate Constipation with Fecal Retention in a 21-Month-Old
For a 21-month-old with moderate constipation and fecal retention, begin with disimpaction using glycerin suppositories or manual disimpaction, followed immediately by maintenance therapy with polyethylene glycol (PEG) as first-line pharmacologic treatment, combined with dietary modifications including increased fluids and age-appropriate high-fiber foods. 1, 2
Phase 1: Disimpaction (Days to Weeks)
The presence of fecal retention requires addressing the impaction before maintenance therapy can be effective 2, 3:
- Glycerin suppositories are the recommended first-line option for disimpaction in this age group 1, 2
- Manual disimpaction may be performed if suppositories are insufficient 2
- Critical pitfall to avoid: Do not rely solely on dietary changes without addressing the impaction first, as this will worsen the constipation 2
Phase 2: Maintenance Pharmacologic Therapy (Months to Years)
Once disimpaction is achieved, immediately begin maintenance therapy 2, 3:
- Polyethylene glycol (PEG) is the first-line maintenance laxative, as it is effective, well-tolerated, and generally produces bowel movements within 1-3 days 2, 4, 3
- Alternative osmotic agents include lactulose or sorbitol-containing fruit juices (prune, pear, or apple juice) 2, 5
- Goal: Achieve one non-forced bowel movement every 1-2 days 2
- Critical pitfall to avoid: Do not use stimulant laxatives as first-line therapy; osmotic agents like PEG should be used instead 2
Phase 3: Dietary and Behavioral Modifications (Concurrent with Pharmacotherapy)
Dietary Interventions
At 21 months, this child should be eating solid foods with specific modifications 6, 2:
- Continue regular diet emphasizing high-fiber foods: starches, cereals, yogurt, fruits, and vegetables 6, 2
- Ensure adequate fluid intake throughout the day 2
- Small amounts of sorbitol-containing fruit juices (prune, pear, apple) can help increase stool frequency and water content 1, 2
- Avoid foods high in simple sugars and fats that can worsen constipation 6, 2
- Consider a trial of withholding cow's milk, as it may promote constipation in some children 5
Behavioral Management
- Establish regular toileting routines appropriate for age 3
- Use reward systems to encourage positive behaviors 3
- Recognize and address withholding behaviors 3
Duration and Follow-Up
Expect prolonged treatment with frequent relapses 3, 5:
- Maintenance therapy may need to continue for months to years before the child regains normal bowel motility and rectal perception 2
- Regular reassessment of bowel habits is essential to monitor treatment effectiveness 1
- Only 50-70% of children demonstrate long-term improvement despite treatment 5
- Critical pitfall to avoid: Parents often cease treatment prematurely before the child regains bowel motility and rectal perception 2
Red Flags Requiring Further Evaluation
While functional constipation is most common, watch for warning signs of organic disease 1, 3:
- Delayed passage of meconium (>48 hours after birth) 1
- Failure to thrive, abdominal distension 1
- Abnormal anal position or absence of anal/cremasteric reflex 1
- Onset before one month of age, explosive stools 3
Treatment Algorithm Summary
- Disimpact first with glycerin suppositories or manual disimpaction 1, 2
- Start PEG immediately after disimpaction as maintenance therapy 2, 4
- Implement dietary changes concurrently: high-fiber foods, adequate fluids, sorbitol-containing juices 6, 2
- Continue maintenance for months, adjusting laxative dosing as needed 2
- Gradually taper medications only after bowel habits normalize 2
- Provide intensive family education about the chronic nature and need for prolonged therapy 3, 5