What is the duration of effectiveness of a Liletta (levonorgestrel-releasing) intrauterine device (IUD)?

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Last updated: March 31, 2025View editorial policy

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From the Guidelines

Liletta IUD is good for 5 years, as approved by the FDA. This hormonal intrauterine device releases 52 mg of levonorgestrel, a progestin hormone, directly into the uterus to prevent pregnancy 1. The device works primarily by thickening cervical mucus to prevent sperm from reaching the egg, thinning the uterine lining, and sometimes preventing ovulation. Some key points to consider about Liletta IUD include:

  • Failure rate: 0.1% within the first year of typical use 1
  • Active ingredient: 52 mg of levonorgestrel 1
  • Length of time approved for use by FDA: 5 years 1 While the device can remain effective for the approved duration, it can be removed earlier if pregnancy is desired or if side effects become problematic. Common side effects may include irregular bleeding, especially in the first few months, cramping, and spotting. The effectiveness rate of Liletta is over 99%, making it one of the most reliable forms of contraception available.

From the Research

Liletta IUD Effectiveness and Duration

  • The Liletta IUD is a type of levonorgestrel-releasing intrauterine device (LNG IUD) that is used for contraception and other gynecological conditions 2, 3, 4, 5, 6.
  • According to the studies, the Liletta IUD is effective for up to 5 years, with a low risk of pregnancy and other complications 3, 6.
  • The device releases 52 mg of levonorgestrel, which is a progestin hormone that helps to prevent pregnancy and reduce menstrual bleeding 5, 6.
  • The studies show that the Liletta IUD is highly effective, with a pregnancy rate of 0.1 per hundred women per year, compared to other types of IUDs 2, 6.

Comparison to Other IUDs

  • The Liletta IUD has been compared to other types of IUDs, including copper IUDs, and has been shown to be more effective in preventing pregnancy and reducing menstrual bleeding 2, 6.
  • The device has also been shown to be effective in reducing dysmenorrhea and other gynecological symptoms, making it a good option for women with these conditions 3, 4.

Safety and Side Effects

  • The studies show that the Liletta IUD is generally safe and well-tolerated, with few side effects reported 5, 6.
  • However, some women may experience hormonal side effects, such as anxiety or depression, and the device may need to be removed in some cases 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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