Diagnostic Criteria for Schizophrenia: PPDGJ, DSM, and APA
Critical Clarification
The question contains a fundamental misunderstanding: PPDGJ (Pedoman Penggolongan dan Diagnosis Gangguan Jiwa - Indonesian psychiatric diagnostic guidelines), DSM (Diagnostic and Statistical Manual of Mental Disorders), and APA (American Psychiatric Association) are not three separate diagnostic systems. The APA publishes the DSM, so they represent the same diagnostic framework. PPDGJ is the Indonesian adaptation that historically aligned with ICD (International Classification of Diseases) criteria 1.
The Two Major Diagnostic Systems
DSM Criteria (American Psychiatric Association)
The DSM-IV and DSM-5 criteria require at least two psychotic symptoms present for a significant period during a 1-month timeframe, with overall disturbance lasting at least 6 months, and marked social/occupational dysfunction 2.
Core Symptom Requirements:
- At least two of the following must be present for a significant portion of a 1-month period: delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior, and negative symptoms (affective flattening, alogia, avolition) 1
- Only one symptom is required if: (1) delusions are bizarre, (2) hallucinations include a voice providing running commentary on the person's behavior or thinking, or (3) two or more voices are conversing with each other 1, 2
- Duration of active symptoms may be less if symptoms resolved with treatment 1
Duration Criterion:
- Total disturbance must persist for at least 6 months, including an active phase of overt psychotic symptoms with or without prodromal or residual phases 1
- If the 6-month criterion is not met, the diagnosis becomes schizophreniform disorder 1
- The 6-month period includes prodromal phase (deteriorating function before psychotic symptoms) and residual phase (following active symptoms) 1
Functional Impairment:
- Marked deterioration in social, occupational, and self-care functioning below the level achieved before onset is required 1
- In children and adolescents, this includes failure to achieve age-appropriate levels of interpersonal, academic, or occupational development 1, 2
Exclusion Criteria:
- Schizoaffective disorder and mood disorders with psychotic features must be ruled out 1
- Substance abuse and general medical conditions must be excluded 1
- This is particularly critical for adolescents with bipolar disorder, as manic episodes frequently include schizophrenia-like symptoms at onset 1
ICD-10 Criteria (Used by PPDGJ)
The ICD-10 diagnostic criteria are similar to DSM-IV except that the diagnosis can be made once sufficient symptoms have been present for a period of 1 month or more, rather than 6 months 1.
Key Difference from DSM:
- The primary distinction is the shorter duration requirement: ICD-10 requires only 1 month of symptoms versus DSM's 6-month requirement 1
- This represents a more liberal diagnostic threshold that allows earlier diagnosis 1
- A study found high diagnostic agreement between DSM-III-R, DSM-IV, and ICD-10 in hospitalized psychotic adolescents, suggesting the systems identify similar patient populations despite the duration difference 1
Practical Diagnostic Approach
Assessment Components:
- Detailed interviews with patient and family members, plus review of past records and historical information are essential 1, 2, 3
- Structured interviews, symptom scales, and diagnostic decision trees (including the DSM manual) serve as important aids to ensure reliability and veracity of diagnosis 1, 3
- Establish the duration, type, number, and combinations of symptoms required for diagnosis, as well as the pattern of symptom development and course of illness 1
Standardized Rating Scales:
- Use validated symptom rating scales such as the Positive and Negative Syndrome Scale (PANSS), Brief Psychiatric Rating Scale (BPRS), Scale for the Assessment of Negative Symptoms (SANS), or Scale for the Assessment of Positive Symptoms (SAPS) 3
- These scales provide inter-rater reliability of 0.85-0.9 when carefully applied 3
Critical Diagnostic Pitfalls
Misdiagnosis Risk:
- Misdiagnosis at initial presentation is extremely common, with many patients initially diagnosed with schizophrenia later found to have bipolar disorder or personality disorders 1, 2, 3
- Approximately 50% of adolescents with bipolar disorder are initially misdiagnosed as having schizophrenia due to florid psychosis at onset 2
- Systematic longitudinal reassessment over time is the only accurate method for distinguishing schizophrenia from bipolar disorder 2
Specific Challenges:
- Most children reporting hallucinations are not schizophrenic and many do not have psychotic disorders 1, 2
- Distinguish formal thought disorder from developmental speech/language disorders 1, 2
- Cultural or religious beliefs may be misinterpreted as psychotic symptoms when taken out of context 2
- Clinicians must actively guard against racial biases, as African-American youth are more likely to be characterized as having psychotic conditions 2
Mandatory Longitudinal Follow-up:
- The diagnosis should be made when diagnostic criteria are met and other illnesses have been adequately ruled out, but patients must be followed longitudinally with periodic diagnostic reassessments to ensure accuracy 1
- Patients often present acutely psychotic before meeting the 6-month criterion, requiring tentative diagnosis with longitudinal confirmation 2