How to Evaluate a Patient
Begin by obtaining a detailed medical history, which establishes the diagnosis in approximately 76% of cases and is the single most critical component of patient evaluation. 1
Essential Components of History Taking
Chief Complaint and Present Illness
- Document the patient's description of their problem in their own words first, then ask targeted questions to clarify 2
- Assess onset (abrupt vs. gradual), duration, severity, and progression of symptoms 2
- Identify associated symptoms including fever, pain characteristics, functional limitations, and systemic manifestations 2
- Evaluate impact on activities of daily living and quality of life 2
Past Medical History
- Review all chronic conditions including cardiovascular disease, diabetes, hypertension, COPD, chronic kidney disease, and psychiatric disorders 2
- Document prior surgeries, hospitalizations, and significant illnesses 2
- Assess for conditions predisposing to specific complications (e.g., immunosuppression, prior gastrectomy, extremes of age) 2
Medication Assessment
- List all current medications including prescription drugs, over-the-counter medications, supplements, and herbal remedies 2
- Specifically identify high-risk medications: vasodilators, diuretics, antipsychotics, sedative/hypnotics, anticoagulants, and antihypertensives 2
- Document recent antibiotic use, antacids, or anti-motility agents 2
Social and Behavioral History
- Tobacco use (quantify pack-years for lung cancer screening consideration) 3
- Alcohol consumption patterns 3
- Occupational exposures and employment status 2
- Living situation, social support, and caregiver availability 2
- Sexual history when relevant (including receptive anal intercourse or oral-anal contact for infectious diarrhea evaluation) 2
Epidemiological Risk Factors
- Recent travel to developing areas 2
- Day-care center attendance or employment 2
- Consumption of unsafe foods (raw meats, eggs, shellfish, unpasteurized products) 2
- Contact with animals, farms, petting zoos, or reptiles 2
- Knowledge of other ill contacts 2
Review of Systems
- Conduct a psychiatric review of systems including anxiety, panic attacks, sleep abnormalities, mood changes, and cognitive concerns 2
- Cardiovascular: chest pain, palpitations, dyspnea, orthopnea, edema 2
- Neurological: headaches, dizziness, syncope, weakness, sensory changes 2
- For specific conditions, tailor questions (e.g., exertional leg symptoms and claudication for PAD evaluation) 2
Physical Examination Priorities
Vital Signs and General Assessment
- Measure blood pressure in both arms, pulse rate, respiratory rate, temperature, and oxygen saturation ("the fifth vital sign") 2
- Perform orthostatic blood pressure measurements (lying, sitting, standing) for patients with falls, syncope, or dizziness 2
- Calculate body mass index and measure waist circumference 2
- Assess general appearance, nutritional status, and level of distress 2, 4
Cardiovascular Examination
- Palpate all peripheral pulses (carotid, brachial, radial, femoral, popliteal, dorsalis pedis, posterior tibial) 2
- Auscultate for carotid, abdominal, and femoral bruits 2
- Assess jugular venous pressure and examine for edema 2
- Perform thorough cardiac auscultation 2
Neurological Assessment
- Evaluate orientation to person, place, time, and situation 4
- Test coordination, gait, and balance (including "get up and go" test for fall risk) 2, 4
- Assess for peripheral neuropathies and proximal motor strength 2
- Check for involuntary movements or abnormalities of motor tone 4
- Evaluate cranial nerves, reflexes, and sensory function 4
Focused Examinations Based on Presentation
- For PAD: inspect legs and feet with all lower garments removed, assess skin temperature, check for ulcers or gangrene 2
- For infectious diarrhea: assess volume depletion (skin turgor, mucous membranes, mental status) 2
- For erectile dysfunction: examine genitalia for testicular abnormalities, penile fibrosis, retractable foreskin 2
- For geriatric patients: complete head-to-toe evaluation even with seemingly isolated injuries 2
Mental Status Examination
- Assess mood, affect, thought process, thought content, and perception 2, 4
- Screen for suicidal ideation (active or passive thoughts) 4
- Evaluate for aggressive or psychotic ideas 4
- Use validated cognitive screening tools (MoCA, Mini-Cog, MMSE) for patients ≥65 years or with cognitive concerns 3, 4
Laboratory and Diagnostic Testing
Principle: Test Selection Based on History and Examination
Order laboratory investigations only after completing history and physical examination, as testing leads to diagnosis in only 11% of cases but increases diagnostic confidence 1
Baseline Screening (Age and Risk-Appropriate)
- Complete blood count if clinically indicated 3
- Comprehensive metabolic panel including electrolytes, renal function, liver function 2
- Fasting glucose or HbA1c for diabetes screening 3
- Lipid panel for cardiovascular risk assessment 3
- Urinalysis when indicated 3
Condition-Specific Testing
- For PAD: ankle-brachial index (ABI), toe-brachial index if ABI abnormal 2
- For hypertension evaluation: ECG, assessment for target organ damage 2
- For infectious diarrhea: stool studies only if bloody diarrhea, fever, severe dehydration, or immunocompromised 2
- For erectile dysfunction: testosterone level if hypogonadism suspected, PSA and rectal exam before hormone therapy 2
Advanced Imaging
- Order imaging based on specific clinical indications from history and examination 5
- Avoid routine surveillance imaging without clinical indication 2
Special Populations
Geriatric Patients (≥65 years)
- Perform comprehensive geriatric assessment including functional status (ADLs, IADLs), fall risk, cognitive screening, and polypharmacy review 2, 3
- Assess for delirium using validated tools if altered mental status present 2
- Evaluate gait and mobility with timed assessments 3
- Screen for depression using standardized instruments 3
Patients with Acute Illness
- Use physiological track-and-trigger systems (e.g., NEWS) to identify deteriorating patients 2
- Assess for signs of sepsis, shock, or organ failure 2
- Determine urgency: emergency (<6 hours), urgent (6-24 hours), or routine 2
Common Pitfalls to Avoid
- Never discontinue oxygen therapy to obtain room air oximetry readings in patients who clearly require supplemental oxygen 2
- Do not rely solely on pulse oximetry in carbon monoxide poisoning (check carboxyhemoglobin levels) 2
- Avoid ordering extensive testing before completing thorough history and examination 6, 1
- Do not overlook medication-related causes of presenting symptoms 2
- Fail to consider cultural factors, language barriers, and education level when interpreting findings 4
- Missing collateral information from family or caregivers, especially in cognitive impairment 4
- Overlooking subtle cognitive deficits in high-functioning elderly patients 4