How to evaluate a patient?

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Last updated: November 19, 2025View editorial policy

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How to Evaluate a Patient

Begin by obtaining a detailed medical history, which establishes the diagnosis in approximately 76% of cases and is the single most critical component of patient evaluation. 1

Essential Components of History Taking

Chief Complaint and Present Illness

  • Document the patient's description of their problem in their own words first, then ask targeted questions to clarify 2
  • Assess onset (abrupt vs. gradual), duration, severity, and progression of symptoms 2
  • Identify associated symptoms including fever, pain characteristics, functional limitations, and systemic manifestations 2
  • Evaluate impact on activities of daily living and quality of life 2

Past Medical History

  • Review all chronic conditions including cardiovascular disease, diabetes, hypertension, COPD, chronic kidney disease, and psychiatric disorders 2
  • Document prior surgeries, hospitalizations, and significant illnesses 2
  • Assess for conditions predisposing to specific complications (e.g., immunosuppression, prior gastrectomy, extremes of age) 2

Medication Assessment

  • List all current medications including prescription drugs, over-the-counter medications, supplements, and herbal remedies 2
  • Specifically identify high-risk medications: vasodilators, diuretics, antipsychotics, sedative/hypnotics, anticoagulants, and antihypertensives 2
  • Document recent antibiotic use, antacids, or anti-motility agents 2

Social and Behavioral History

  • Tobacco use (quantify pack-years for lung cancer screening consideration) 3
  • Alcohol consumption patterns 3
  • Occupational exposures and employment status 2
  • Living situation, social support, and caregiver availability 2
  • Sexual history when relevant (including receptive anal intercourse or oral-anal contact for infectious diarrhea evaluation) 2

Epidemiological Risk Factors

  • Recent travel to developing areas 2
  • Day-care center attendance or employment 2
  • Consumption of unsafe foods (raw meats, eggs, shellfish, unpasteurized products) 2
  • Contact with animals, farms, petting zoos, or reptiles 2
  • Knowledge of other ill contacts 2

Review of Systems

  • Conduct a psychiatric review of systems including anxiety, panic attacks, sleep abnormalities, mood changes, and cognitive concerns 2
  • Cardiovascular: chest pain, palpitations, dyspnea, orthopnea, edema 2
  • Neurological: headaches, dizziness, syncope, weakness, sensory changes 2
  • For specific conditions, tailor questions (e.g., exertional leg symptoms and claudication for PAD evaluation) 2

Physical Examination Priorities

Vital Signs and General Assessment

  • Measure blood pressure in both arms, pulse rate, respiratory rate, temperature, and oxygen saturation ("the fifth vital sign") 2
  • Perform orthostatic blood pressure measurements (lying, sitting, standing) for patients with falls, syncope, or dizziness 2
  • Calculate body mass index and measure waist circumference 2
  • Assess general appearance, nutritional status, and level of distress 2, 4

Cardiovascular Examination

  • Palpate all peripheral pulses (carotid, brachial, radial, femoral, popliteal, dorsalis pedis, posterior tibial) 2
  • Auscultate for carotid, abdominal, and femoral bruits 2
  • Assess jugular venous pressure and examine for edema 2
  • Perform thorough cardiac auscultation 2

Neurological Assessment

  • Evaluate orientation to person, place, time, and situation 4
  • Test coordination, gait, and balance (including "get up and go" test for fall risk) 2, 4
  • Assess for peripheral neuropathies and proximal motor strength 2
  • Check for involuntary movements or abnormalities of motor tone 4
  • Evaluate cranial nerves, reflexes, and sensory function 4

Focused Examinations Based on Presentation

  • For PAD: inspect legs and feet with all lower garments removed, assess skin temperature, check for ulcers or gangrene 2
  • For infectious diarrhea: assess volume depletion (skin turgor, mucous membranes, mental status) 2
  • For erectile dysfunction: examine genitalia for testicular abnormalities, penile fibrosis, retractable foreskin 2
  • For geriatric patients: complete head-to-toe evaluation even with seemingly isolated injuries 2

Mental Status Examination

  • Assess mood, affect, thought process, thought content, and perception 2, 4
  • Screen for suicidal ideation (active or passive thoughts) 4
  • Evaluate for aggressive or psychotic ideas 4
  • Use validated cognitive screening tools (MoCA, Mini-Cog, MMSE) for patients ≥65 years or with cognitive concerns 3, 4

Laboratory and Diagnostic Testing

Principle: Test Selection Based on History and Examination

Order laboratory investigations only after completing history and physical examination, as testing leads to diagnosis in only 11% of cases but increases diagnostic confidence 1

Baseline Screening (Age and Risk-Appropriate)

  • Complete blood count if clinically indicated 3
  • Comprehensive metabolic panel including electrolytes, renal function, liver function 2
  • Fasting glucose or HbA1c for diabetes screening 3
  • Lipid panel for cardiovascular risk assessment 3
  • Urinalysis when indicated 3

Condition-Specific Testing

  • For PAD: ankle-brachial index (ABI), toe-brachial index if ABI abnormal 2
  • For hypertension evaluation: ECG, assessment for target organ damage 2
  • For infectious diarrhea: stool studies only if bloody diarrhea, fever, severe dehydration, or immunocompromised 2
  • For erectile dysfunction: testosterone level if hypogonadism suspected, PSA and rectal exam before hormone therapy 2

Advanced Imaging

  • Order imaging based on specific clinical indications from history and examination 5
  • Avoid routine surveillance imaging without clinical indication 2

Special Populations

Geriatric Patients (≥65 years)

  • Perform comprehensive geriatric assessment including functional status (ADLs, IADLs), fall risk, cognitive screening, and polypharmacy review 2, 3
  • Assess for delirium using validated tools if altered mental status present 2
  • Evaluate gait and mobility with timed assessments 3
  • Screen for depression using standardized instruments 3

Patients with Acute Illness

  • Use physiological track-and-trigger systems (e.g., NEWS) to identify deteriorating patients 2
  • Assess for signs of sepsis, shock, or organ failure 2
  • Determine urgency: emergency (<6 hours), urgent (6-24 hours), or routine 2

Common Pitfalls to Avoid

  • Never discontinue oxygen therapy to obtain room air oximetry readings in patients who clearly require supplemental oxygen 2
  • Do not rely solely on pulse oximetry in carbon monoxide poisoning (check carboxyhemoglobin levels) 2
  • Avoid ordering extensive testing before completing thorough history and examination 6, 1
  • Do not overlook medication-related causes of presenting symptoms 2
  • Fail to consider cultural factors, language barriers, and education level when interpreting findings 4
  • Missing collateral information from family or caregivers, especially in cognitive impairment 4
  • Overlooking subtle cognitive deficits in high-functioning elderly patients 4

Documentation Requirements

  • Record all findings systematically including negative pertinent findings 2
  • Document inspired oxygen device and flow rate with oxygen saturation readings 2
  • Note patient's own description of symptoms verbatim when possible 2
  • Include assessment of suicide risk or aggressive behavior risk when relevant 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Annual Wellness Exam Recommendations for 75-Year-Old Males

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Brief Mental Status Examination Components

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

The Outpatient Physical Examination.

The Medical clinics of North America, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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