Cost of Talicia for 14-Day Treatment
Talicia costs approximately $700 for a 14-day course in the United States, with or without discount coupons such as GoodRx. 1
Cost Breakdown and Context
- Talicia retail price: $700 for the complete 14-day treatment course 1
- Discount availability: Unlike many medications, GoodRx coupons do not reduce the cost of Talicia—it remains $700 with or without such coupons 1
Cost Comparison with Generic Components
Talicia is significantly more expensive than prescribing its individual generic components separately:
- Generic rifabutin alone: ~$400 retail, but can be obtained for ~$150 with GoodRx coupons 1
- Generic amoxicillin: Relatively inexpensive (typically <$20 for a 14-day course)
- Generic PPI (omeprazole/esomeprazole): Typically $10-30 for a 14-day course
Total cost of generic components: Approximately $180-200 with discount coupons, compared to $700 for the branded Talicia formulation 1
Clinical Considerations
- Talicia is a combination formulation containing rifabutin, amoxicillin, and high-dose PPI in a single package 1
- Theoretical advantage: Rifabutin resistance is rare, making this an effective empiric therapy option 1
- Clinical experience: Limited but encouraging data support its use for H. pylori eradication 1
Important Caveats
- Cost barrier: The $700 price point represents a significant financial burden compared to generic alternatives that cost 70-75% less 1
- Insurance coverage: Varies widely; many plans may require prior authorization or may not cover branded formulations when generic alternatives exist
- Patient assistance programs: May be available directly from the manufacturer for eligible patients