Vuity Dosage Frequency
Vuity (pilocarpine 1.25%) eyedrops are used once daily in each eye. 1
Standard Dosing Regimen
The FDA-approved dosing for pilocarpine ophthalmic solution varies by indication and concentration:
- For presbyopia (Vuity 1.25%): One drop in each affected eye once daily 2
- For glaucoma (higher concentrations): One to two drops may be repeated up to three or four times daily, depending on severity and patient response 1
Key Administration Points
Vuity specifically targets presbyopia and requires only once-daily dosing, which represents a significant adherence advantage over traditional glaucoma formulations of pilocarpine that require multiple daily doses. 2
Proper Technique Considerations
- Patients should be instructed on eyelid closure or nasolacrimal occlusion after instillation to reduce systemic absorption 3
- Repeated instruction on proper drop instillation technique improves outcomes, as many patients struggle with correct administration 3
- Linking drop administration to a specific daily activity enhances adherence 3
Clinical Effects Timeline
- Peak effect occurs 1-2 hours after instillation, when near vision improvement and pupil constriction are maximal 2
- The medication provides improved near vision while maintaining stable distance vision 2
- Both amplitude of accommodation and pupil size changes are measurable within this timeframe 2
Important Caveats
The once-daily dosing of Vuity differs substantially from traditional pilocarpine formulations used for glaucoma, which require 3-4 times daily administration due to higher concentrations (typically 1-4%) and different therapeutic goals. 1 Do not confuse these regimens—Vuity's lower concentration (1.25%) and presbyopia indication necessitate only once-daily use.