Do tonsillitis and pharyngitis use the same Centor (Center for Disease Control and Prevention) score?

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Last updated: November 20, 2025View editorial policy

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Yes, Both Tonsillitis and Pharyngitis Use the Same Centor Scoring System

The Centor score is applied to acute sore throat presentations regardless of whether the inflammation primarily involves the tonsils (tonsillitis) or the pharynx (pharyngitis), as both conditions are part of the same clinical spectrum of group A streptococcal infection. 1

Why the Same Scoring System Applies

The Centor criteria were developed to assess the likelihood of group A streptococcal infection in patients presenting with acute sore throat, which encompasses both pharyngitis and tonsillitis as overlapping clinical presentations. 2, 3 The guideline literature consistently refers to "acute sore throat," "pharyngitis," and "tonsillitis" interchangeably when discussing the Centor score application. 1

In fact, one of the four Centor criteria specifically evaluates tonsillar exudate, demonstrating that tonsillitis is inherently incorporated into the scoring system. 2, 3 The four components are:

  • Fever by history (1 point) 2
  • Tonsillar exudates (1 point) 2
  • Tender anterior cervical lymphadenopathy (1 point) 2
  • Absence of cough (1 point) 2

Clinical Application

The European guideline for acute sore throat management explicitly states that the Centor score helps identify patients with higher likelihood of group A streptococcal infection, whether presenting with pharyngitis or tonsillitis. 1 A German guideline on tonsillitis specifically recommends using the Centor or McIsaac scoring system to estimate the probability of β-hemolytic streptococcal tonsillitis. 4

Risk Stratification Remains Identical

The risk stratification based on Centor score applies equally to both conditions:

  • Score 0-2: Low probability (1-17% risk of GAS), no testing or antibiotics recommended 2, 3
  • Score 3-4: Higher probability (28-53% risk of GAS), consider rapid antigen testing 2, 3

Important Clinical Caveat

The Centor score was validated only in adults, not children, so its utility is lower in pediatric populations regardless of whether the presentation is labeled as pharyngitis or tonsillitis. 2 The modified McIsaac score adds age stratification for broader applicability across age groups. 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Diagnosing Streptococcal Pharyngitis with Centor Criteria

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Centor Score for Diagnosing Group A Streptococcal Pharyngitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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