What's the next step for a patient with a testis in the superficial inguinal ring, normal testosterone, and normal semen analysis: orchidectomy or another procedure?

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Management of Testis in Superficial Inguinal Ring with Normal Testosterone and Semen Analysis

In an adult patient with a testis in the superficial inguinal ring who has normal testosterone levels and normal semen analysis, orchidectomy is the recommended treatment rather than orchidopexy. 1

Rationale for Orchidectomy Over Orchidopexy

The European Association of Urology provides a strong recommendation for orchidectomy in adult men with unilateral undescended testis who have normal hormonal function and spermatogenesis 1. This recommendation is based on several critical factors:

Why Orchidectomy is Preferred

  • Malignancy risk: Adults with undescended testes have a 3.7 to 7.5-fold increased risk of testicular cancer, with seminoma being the most common tumor type in undescended testes 2. The risk remains elevated even after orchidopexy 3.

  • Fertility preservation: Since the patient has normal semen analysis and normal testosterone, the contralateral descended testis is functioning adequately 1. Men with unilateral cryptorchidism who undergo orchidectomy (monorchidism) have paternity rates similar to those with unilateral cryptorchidism (89.5% vs 94% in controls), indicating no significant fertility disadvantage 3.

  • No functional benefit from orchidopexy: Attempting orchidopexy when orchidectomy is indicated provides no benefit and only increases the cancer surveillance burden 1. Post-pubertal undescended testes typically show severe degenerative changes with considerable loss of spermatogenesis 4.

Critical Procedures Required at Surgery

Simultaneous testicular biopsy must be performed at the time of orchidectomy to detect intratubular germ cell neoplasia (testicular intraepithelial neoplasia/TIN) 1. This is a strong recommendation because:

  • 2-5% of testicular cancer patients have TIN in the contralateral testis 3
  • The highest risk (≥34%) occurs with testicular atrophy (volume <12 ml) and age <40 years 3
  • If untreated, invasive testicular tumor develops in 70% of TIN-positive testes within 7 years 3

Sperm cryopreservation should be offered before orchidectomy to preserve future fertility options, even though current semen analysis is normal 1, 3.

When Orchidopexy Would Be Considered Instead

Orchidopexy is only offered in adults with undescended testis when there is biochemical hypogonadism or spermatogenic failure, and only if technically feasible 1. Since your patient has normal testosterone and normal semen analysis, this does not apply.

Common Pitfalls to Avoid

  • Do not attempt orchidopexy in this clinical scenario—it provides no benefit and increases cancer surveillance burden 1
  • Do not omit testicular biopsy at the time of surgery, as this is the only opportunity to detect pre-malignant changes in the contralateral testis 1
  • Do not consider hormonal treatment—the European Association of Urology strongly recommends against hormonal treatment for cryptorchidism in postpubertal men due to limited efficacy and potential risks 1

Surgical Approach

If orchidectomy is performed, use an inguinal approach with removal of the testis and spermatic cord at the level of the internal inguinal ring 3. Never use a scrotal approach for suspected pathology in undescended testes 5.

References

Guideline

Management of Undescended Testis in Adults

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Results of orchiopexy for the undescended testis.

World journal of urology, 2006

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Undescended testes and puberty. Orchidopexia or orchiectomy.

Zeitschrift fur Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft fur Kinderchirurgie = Surgery in infancy and childhood, 1984

Guideline

Management of Testicular Tumors in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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