Do I need a tetanus (Td) shot after a cat bite?

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Tetanus Prophylaxis After Cat Bite

Yes, you need a tetanus shot after a cat bite if your last tetanus vaccination was 5 or more years ago. Cat bites are classified as contaminated, tetanus-prone wounds requiring appropriate prophylaxis based on your immunization history. 1, 2

Why Cat Bites Are High-Risk

  • Cat bites are classified as "other wounds" (non-clean wounds) that may be contaminated with dirt, feces, soil, or saliva—similar to puncture wounds and avulsions. 2
  • Cats are coprophagic (feces-eating) animals, which increases the potential risk of tetanus transmission through their bites and scratches. 2
  • While rare, tetanus cases have been documented after cat scratches and bites, even in previously immunized patients. 3

Tetanus Prophylaxis Algorithm Based on Your Vaccination Status

If Your Last Tetanus Shot Was <5 Years Ago:

  • No tetanus vaccine or tetanus immune globulin (TIG) is needed. 1, 2
  • Proper wound care alone is sufficient. 4

If Your Last Tetanus Shot Was ≥5 Years Ago:

  • You need a tetanus toxoid-containing vaccine (no TIG required). 1, 2
  • For persons aged ≥11 years who have not previously received Tdap or whose Tdap history is unknown, Tdap is preferred over Td. 1
  • For persons with documented previous Tdap vaccination, either Td or Tdap may be used. 2

If You Have Unknown or Incomplete Vaccination History (<3 Doses):

  • You need both a tetanus toxoid-containing vaccine AND TIG (250 units intramuscularly). 1, 4
  • These should be administered using separate syringes at different anatomical sites. 4
  • You must complete the 3-dose primary series: first two doses at least 4 weeks apart, third dose 6-12 months after the second. 1

Special Populations

Pregnant Women:

  • Tdap should be used regardless of prior Tdap history if tetanus prophylaxis is indicated. 1, 2

Immunocompromised Patients:

  • Persons with HIV infection or severe immunodeficiency who have contaminated wounds should receive TIG regardless of their tetanus immunization history. 1, 2

History of Arthus Reaction:

  • Patients with a history of severe Arthus hypersensitivity reaction following a previous tetanus toxoid-containing vaccine should not receive tetanus vaccine until >10 years after the most recent dose, regardless of wound condition. 2, 4

Critical Wound Management

  • Thorough wound cleaning and debridement are essential first steps to remove debris that might harbor Clostridium tetani spores. 4
  • Surgical debridement of necrotic tissue is necessary for wounds that might create anaerobic conditions favorable for bacterial growth. 4
  • The vaccine provides protection against future injuries, not the current one, but should still be administered when indicated. 5

Common Pitfalls to Avoid

  • Do not assume cat bites are "clean wounds"—they must be treated as contaminated wounds requiring appropriate tetanus prophylaxis. 2
  • Do not delay wound care while waiting for vaccination records; if history is uncertain, treat as unvaccinated. 1
  • Remember that complete primary vaccination is nearly 100% effective in preventing tetanus, and protective antibody levels develop rapidly after a booster dose. 1, 4
  • Even with proper childhood immunization and a booster 5 years prior, tetanus can still occur if appropriate prophylaxis is not given after high-risk exposure. 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Tetanus Prophylaxis for Cat Scratches

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

[Tetanus after cat scratch and bites in a previously immunized patient].

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2017

Guideline

Tetanus Management Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Tetanus and trauma: a review and recommendations.

The Journal of trauma, 2005

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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