What is the main ingredient in Nurtec (rimegepant)?

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Last updated: November 20, 2025View editorial policy

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Nurtec ODT Ingredients

Active Ingredient

The active ingredient in Nurtec ODT is rimegepant, a calcitonin gene-related peptide (CGRP) receptor antagonist. 1

Inactive Ingredients

Nurtec ODT contains the following inactive ingredients 1:

  • Benzyl alcohol
  • Eucalyptol
  • Gelatin
  • Limonene
  • Mannitol
  • Menthol
  • Menthone
  • Menthyl acetate
  • Sucralose
  • Vanillin

Formulation Details

  • Rimegepant is available as a 75 mg orally disintegrating tablet (ODT), which dissolves on or under the tongue without the need for water. 1, 2

  • The ODT formulation offers convenience and potentially faster response time compared to conventional tablet formulations. 2

Clinical Context

  • Rimegepant is FDA-approved for both acute treatment of migraine attacks and preventive treatment of episodic migraine in adults. 1, 2

  • For acute treatment, rimegepant can be taken once daily as needed, with no more than 1 tablet in 24 hours and not exceeding 18 doses in 30 days. 1

  • For preventive treatment, rimegepant is taken once every other day. 1

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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