What is the current evidence for the efficacy and safety of VMS-986489 (trial drug) in oncology patients?

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Last updated: November 21, 2025View editorial policy

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VMS-986489: No Available Evidence

There is no available evidence for VMS-986489 as an oncology trial drug in the provided literature or in established medical databases.

Search Results

After comprehensive review of the provided evidence base, which includes:

  • Multiple ASCO clinical practice guidelines on venous thromboembolism in cancer patients 1
  • Treatment guidelines for cancer-associated thrombosis 1
  • ESMO guidelines on cancer pain management 1
  • SIO-ASCO guidelines on integrative oncology 1
  • NCCN-based guidelines on small cell lung cancer treatment 2, 3
  • Various research studies on cancer treatments 4, 5, 6, 7, 8

No references to VMS-986489 were identified in any guideline, drug label, or research publication.

Important Clarifications

  • The abbreviation "VMS" in the medical literature refers to vasomotor symptoms (hot flashes/night sweats), particularly in cancer survivors 8
  • "VMS" also refers to video-mediastinoscopy, a surgical staging procedure for lung cancer 4
  • "VM-26" is the designation for teniposide, an established chemotherapy agent used in lymphomas and leukemias 5, 6, 7

Recommendation

If you are seeking information about a specific investigational oncology agent, verify the correct drug name and trial identifier (such as NCT number) to enable accurate evidence retrieval. The designation "VMS-986489" does not correspond to any known oncology therapeutic in current medical literature or clinical trial databases as of the evidence provided.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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