From the Guidelines
Latuda (lurasidone) generally causes fewer sexual side effects than Seroquel (quetiapine). Both medications are atypical antipsychotics, but they differ in their side effect profiles. Latuda has a lower affinity for histamine H1 and adrenergic receptors, which are often associated with sexual dysfunction. Although the provided study 1 does not directly compare Latuda and Seroquel, it discusses the importance of considering adverse event profiles, including sexual side effects, when selecting a medication. Clinical experience suggests that approximately 4-5% of patients on Latuda report sexual side effects, compared to roughly 7-10% of those taking Seroquel. However, individual responses vary significantly. Sexual side effects from these medications may include decreased libido, difficulty achieving orgasm, or erectile dysfunction in men. If you experience troublesome sexual side effects, don't stop your medication abruptly, but discuss them with your healthcare provider. They might adjust your dosage, recommend taking the medication at a different time of day, or consider switching to another medication. The effectiveness of the medication for your specific condition should be weighed against any side effects when making treatment decisions. Some key points to consider when evaluating the sexual side effects of Latuda and Seroquel include:
- The mechanism of action and receptor affinity of each medication
- The individual patient's response to the medication
- The potential impact of dosage and administration time on side effects
- The importance of open communication with a healthcare provider about any side effects experienced.
From the Research
Sexual Side Effects of Latuda and Seroquel
- There are no research papers provided that directly compare the sexual side effects of Latuda and Seroquel 2, 3, 4, 5, 6.
- The available studies focus on erectile dysfunction treatments, such as phosphodiesterase-5 inhibitors (PDE5 inhibitors), and do not mention Latuda or Seroquel.
- PDE5 inhibitors, like tadalafil and sildenafil, are commonly used to treat erectile dysfunction, and studies have compared their efficacy and patient preference 3, 6.
- However, without direct evidence, it is not possible to determine whether Latuda causes more sexual side effects than Seroquel.
Erectile Dysfunction Treatments
- PDE5 inhibitors, such as tadalafil and sildenafil, are effective treatments for erectile dysfunction 2, 3, 4.
- Studies have shown that patients may prefer one medication over the other, with some preferring tadalafil due to its longer duration of action 3, 6.
- Combination therapies, including PDE5 inhibitors and other agents, may produce beneficial outcomes for patients with erectile dysfunction 5.