How to Write an Order for Thyroid Ultrasound
Order "high-frequency ultrasound of thyroid and central neck" with specific instructions to evaluate nodule characteristics using standardized terminology and include assessment of cervical lymph nodes. 1, 2
Essential Components of the Order
Basic Order Format
- Write: "High-frequency ultrasound of thyroid and central neck" as the primary order 1, 2
- Specify bilateral thyroid evaluation to assess both lobes and the isthmus 3
- Include "with Doppler" if evaluating for thyroiditis or assessing nodule vascularity patterns 2
Required Clinical Information to Include
Indication-specific details:
- State the specific clinical indication (e.g., "palpable thyroid nodule," "abnormal TSH," "family history of thyroid cancer") 2
- Include relevant TSH level if already obtained, as this guides the radiologist's interpretation 2, 4
- Note any history of head/neck irradiation, family history of thyroid cancer, or rapid growth—these are high-risk features that lower the threshold for further intervention 1, 2
Anatomic specifications:
- Request evaluation of "thyroid and central neck (level VI)" to assess for central compartment lymphadenopathy 3
- Add "with lateral neck ultrasound (levels II-V)" if there is clinical suspicion for lymph node involvement or if the nodule is >1 cm with suspicious features 3, 1
Critical Instructions for the Radiologist
Specify nodule characterization requirements:
- Request "characterization using standardized TIRADS terminology" to ensure consistent reporting of suspicious features 1, 5
- Ask for documentation of: composition (solid vs. cystic), echogenicity, margins, presence/absence of microcalcifications, vascularity pattern, and shape (taller-than-wide) 1, 2, 6
- Request measurement of all nodules ≥5 mm in maximal diameter 1
Lymph node assessment:
- Specify "evaluate for suspicious cervical lymphadenopathy" including assessment of size, shape, echogenicity, presence of cystic changes, microcalcifications, and abnormal vascularity 3, 1
Common Clinical Scenarios and Order Modifications
For Known or Suspected Thyroid Nodule
- Standard order: "High-frequency ultrasound of thyroid and central neck with characterization of nodule(s) using TIRADS criteria" 1, 2
- If nodule >1 cm or multiple suspicious features: Add "with lateral neck ultrasound to evaluate for lymphadenopathy" 1
For Thyrotoxicosis (Low TSH)
- Order: "High-frequency Doppler ultrasound of thyroid" to evaluate morphology and vascularity patterns that differentiate Graves disease from destructive thyroiditis 2
- Note: This should be followed by radioiodine uptake scan if etiology remains unclear 2
For Suspected Thyroiditis with Palpable Abnormality
- Order: "High-frequency Doppler ultrasound of thyroid" to differentiate overactive thyroid from destructive thyroiditis and to exclude coexisting malignancy 2
For High-Risk Patients (Radiation History, Family History)
- Order: "High-frequency ultrasound of thyroid, central neck, and bilateral lateral neck" as screening threshold is lower 2
- Explicitly state the risk factor in the indication 2
What NOT to Order
Avoid these common pitfalls:
- Do not order CT or MRI as initial imaging—ultrasound is the only appropriate first-line modality for thyroid nodule characterization 1, 2
- Do not order radioiodine scan in euthyroid patients for malignancy assessment—it does not help determine malignancy risk 2
- Do not order "thyroid scan" when you mean ultrasound—these are different modalities with different indications 2
Follow-Up Based on Results
If ultrasound reveals nodule ≥1 cm with suspicious features:
- Next step is ultrasound-guided fine-needle aspiration (FNA) of the nodule and any suspicious lymph nodes 1
- Suspicious features include: microcalcifications, marked hypoechogenicity, irregular margins, absence of halo, central hypervascularity, or taller-than-wide shape 1, 2, 6
If nodule <1 cm: