Treatment of Supraventricular Tachycardia (SVT)
Begin with vagal maneuvers as first-line therapy, followed immediately by adenosine if unsuccessful, and proceed to synchronized cardioversion for hemodynamically unstable patients or those who fail pharmacological therapy. 1
Acute Management Algorithm
Step 1: Hemodynamic Assessment and Initial Intervention
For all hemodynamically stable patients, initiate vagal maneuvers immediately 1:
- Modified Valsalva maneuver: Patient bears down against a closed glottis for 10-30 seconds (equivalent to 30-40 mm Hg intrathoracic pressure), then immediately lies flat with legs raised 1, 2
- Carotid sinus massage: Apply steady pressure over the right or left carotid sinus for 5-10 seconds after confirming absence of bruit by auscultation 1
- Diving reflex: Apply ice-cold, wet towel to the face 1
- Success rate is approximately 27.7% when switching between techniques, with Valsalva being more successful than carotid massage 1
- Critical caveat: Never apply pressure to the eyeball—this practice is dangerous and abandoned 1
Step 2: Pharmacological Therapy (if vagal maneuvers fail)
Adenosine is the first-line medication 1:
- Dosing: 6 mg rapid IV bolus followed by saline flush; if unsuccessful, give 12 mg 2
- Effectiveness: Terminates AVNRT in approximately 90-95% of patients 1, 2
- Dual role: Functions as both therapeutic and diagnostic agent, unmasking atrial activity in flutter or atrial tachycardia 1
Alternative pharmacological agents for hemodynamically stable patients 1:
- IV diltiazem or verapamil: Particularly effective with 80-98% success rates 1
- IV beta blockers: Reasonable alternative with excellent safety profile, though less effective than calcium channel blockers 1
- Important warning: Avoid diltiazem, verapamil, and beta blockers in patients with suspected ventricular tachycardia, pre-excited atrial fibrillation, or systolic heart failure—these patients may become hemodynamically unstable or develop ventricular fibrillation 1
Step 3: Electrical Cardioversion
Synchronized cardioversion is mandatory for hemodynamically unstable patients 1:
- Perform immediately when adenosine and vagal maneuvers fail or are not feasible 1
- Highly effective in terminating SVT (including AVRT and AVNRT) 1
For hemodynamically stable patients, synchronized cardioversion is indicated when 1:
- Pharmacological therapy fails to terminate the tachycardia 1
- Pharmacological therapy is contraindicated 1
- A second drug bolus or higher dose may be attempted before proceeding to cardioversion 1
Long-Term Management
First-Line Ongoing Therapy
Oral beta blockers, diltiazem, or verapamil are the first-line options for ongoing management 1, 2:
- Recommended for symptomatic SVT patients without ventricular pre-excitation during sinus rhythm 1
- Beta blockers are specifically recommended as first-line by the American College of Cardiology 2
- Calcium channel blockers serve as alternatives to beta blockers 2
Catheter Ablation
Catheter ablation is the definitive curative option 1, 2, 3:
- Success rates: 94.3% to 98.5% for single procedure 3
- Indications: Frequent symptomatic episodes, poor tolerance or ineffectiveness of medications, or patient preference for non-pharmacological approach 2
- Recommended as first-line therapy to prevent recurrence 3
- All patients treated for SVT should be referred for heart rhythm specialist opinion 4
Alternative Pharmacological Agents
For patients who are not candidates for or prefer not to undergo catheter ablation 1:
- Flecainide or propafenone: Reasonable for patients without structural heart disease or ischemic heart disease 1, 5
- Sotalol: May be reasonable when first-line agents fail 1
- Dofetilide: May be reasonable when beta blockers, diltiazem, flecainide, propafenone, or verapamil are ineffective or contraindicated 1
- Amiodarone: May be considered when all other agents are ineffective or contraindicated 1
- Digoxin: May be reasonable for patients without pre-excitation 1
Special Populations
Pregnancy
Vagal maneuvers remain first-line and are safe during pregnancy 2:
- Adenosine is considered safe due to its short half-life 2
- Synchronized cardioversion can be performed safely at all stages of pregnancy if necessary 2
Pre-excitation Syndromes
Avoid AV nodal blocking agents in patients with pre-excitation 2:
- Do not use adenosine, beta blockers, calcium channel blockers, or digoxin in pre-excited atrial fibrillation 2
- Consider ibutilide or IV procainamide for hemodynamically stable pre-excited AF 2
- Use synchronized cardioversion for hemodynamically unstable patients 6