Is foot and ankle surgery considered low-risk?

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Last updated: November 21, 2025View editorial policy

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Is Foot and Ankle Surgery Considered Low-Risk?

Foot and ankle surgery cannot be universally classified as low-risk; the risk profile varies substantially based on patient comorbidities, with diabetic patients—particularly those with neuropathy or Charcot neuro-osteoarthropathy—facing significantly elevated complication rates including surgical site infection (9.5%), wound dehiscence, hardware failure, and amputation risk. 1

Risk Stratification by Patient Population

High-Risk Populations

Diabetic patients with neuropathy undergoing foot and ankle surgery face a 9.5% post-operative surgical site infection rate, which represents a substantially elevated baseline risk compared to general surgical populations. 1

Patients with diabetes and Charcot neuro-osteoarthropathy (CNO) experience dramatically higher complication rates, including:

  • Significantly elevated amputation rates compared to diabetic patients without CNO 1
  • Increased hardware removal requirements 1
  • Higher rates of wound dehiscence 1
  • Acute kidney injury and pneumonia complications 1
  • A 6-12 fold increased risk of major amputation when deformity leads to ulceration 1, 2

Moderate-Risk Populations

Diabetic transplant patients do not show increased surgical complication rates (OR 0.83,95% CI 0.33-2.08) compared to diabetic patients without transplantation, though they demonstrate higher mortality from non-surgical causes during follow-up (14.3% mortality rate). 3

Adult patients with neuromuscular diseases (including cerebral palsy) demonstrate complication rates similar to average populations, with overall wound complication rates of 10%, infection rates of 8%, and nonunion rates of 10% following arthrodesis. 4

Specific Procedure-Related Complications

Surgical Offloading Procedures

Achilles tendon lengthening (ATL) carries specific transfer ulcer risks, with heel ulcer development occurring in 13-15% of patients at 12-24 months follow-up, and up to 47% risk in patients with heel anesthesia and significant post-operative dorsiflexion. 1

Metatarsal head resection procedures demonstrate variable transfer ulcer rates, ranging from 0% to 41% depending on the study, with single metatarsal head resection showing the highest risk (41% at 13.1 months average follow-up). 1

Reconstructive Surgery for CNO

CNO reconstruction is associated with high complication rates requiring careful risk-benefit analysis before surgical intervention, including surgical site infection, wound dehiscence, non-union, and hardware failure. 1

Critical Risk Factors to Assess

Before classifying any foot and ankle surgery as low-risk, evaluate these specific factors:

  • Peripheral neuropathy status: Loss of protective sensation dramatically increases complication risk 5, 6
  • Peripheral arterial disease: Poor circulation impairs healing and increases infection risk 5
  • Active Charcot neuro-osteoarthropathy: Represents a contraindication or requires specialized surgical approach 1, 2
  • Foot deformities: Increase technical difficulty and complication potential 5
  • History of prior ulceration or amputation: Indicates high-risk status 5, 6

Common Pitfalls in Risk Assessment

Do not assume foot and ankle surgery is uniformly low-risk based solely on the anatomic location or procedure type—patient-specific factors are the primary determinants of surgical risk. 1

Avoid underestimating the inflammatory burden in active CNO, where surgery on an acutely inflamed foot carries substantially higher complication rates than surgery during remission phase. 1

Never overlook vascular status before any surgical intervention, as inadequate perfusion fundamentally compromises healing regardless of surgical technique. 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Charcot Foot: Definition, Clinical Implications, and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Outcomes of Foot and Ankle Surgery in Diabetic Patients Who Have Undergone Solid Organ Transplantation.

The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons, 2015

Guideline

Management of Ingrown Toenails in Diabetic Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Diabetic Blister on Toe

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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