Treatment for Corneal Foreign Body
Irrigate the eye with sterile saline to flush loose material, remove the foreign body under slit-lamp visualization, prescribe broad-spectrum topical antibiotic prophylaxis (moxifloxacin or gatifloxacin four times daily), and ensure ophthalmology follow-up within 24-48 hours. 1
Immediate Assessment and Red Flags
Before attempting removal, assess for features requiring urgent ophthalmology referral:
- Test visual acuity immediately to establish baseline function and identify acute vision loss 1
- High-velocity mechanisms (grinding, metal work, nailing) carry higher risk of globe penetration and require immediate specialist evaluation 2, 1
- Irregular pupil after trauma indicates penetrating injury requiring emergency referral 2, 1
- Eye bleeding, vision loss, or visible corneal damage (ulceration, haze, opacity, purulent discharge) are critical red flags 1
- Contact lens-related injuries require immediate lens removal and discontinuation 2, 1
Initial Management for Low-Energy Foreign Bodies
For superficial foreign bodies without penetration:
- Do not rub the eye, as this embeds the foreign body deeper and causes corneal abrasion 2
- Irrigate with sterile saline to flush loose material first 1
- Allow natural tears or use tap water/commercial eye wash for initial flushing 2, 1
- Shield the eye with a hard plastic eye shield, paper cup, or plastic cup to prevent unintentional touching 2, 1
Foreign Body Removal Technique
Under slit-lamp biomicroscopy, evaluate:
- Corneal epithelium for defects, location of foreign body (central vs peripheral), depth, and presence of rust ring 3
- Fluorescein staining to identify epithelial defects and differentiate from pooling in areas of thinning 3
- Evert the eyelid to inspect tarsal conjunctiva for retained foreign bodies 3
- Remove the foreign body atraumatically under magnification 4
- Eliminate rust rings if metallic foreign body present, as incomplete removal requires reassessment 1, 4
Post-Removal Treatment Protocol
Mandatory pharmacologic management includes:
- Broad-spectrum topical antibiotic prophylaxis: moxifloxacin or gatifloxacin four times daily 1
- Topical NSAID (ketorolac) for pain, photophobia, and foreign body sensation 1
- Cycloplegic agent (cyclopentolate) to reduce ciliary spasm pain 1
- Oral acetaminophen or NSAIDs for additional pain relief 2, 1
Critical Pitfalls to Avoid
- Never prescribe topical corticosteroids, which promote ulceration from fungal contaminants and can cause corneal melting and perforation 5, 4
- Never prescribe topical anesthetics for home use, as they mask pain from retained foreign bodies or developing corneal ulcers 4
- Test corneal sensitivity in all patients, as corneal anesthesia enhances risk of melting and perforation 5
- Avoid protective patching in contact lens-related injuries due to infection risk 1
Mandatory Follow-Up Requirements
- All patients require ophthalmology follow-up within 24-48 hours to monitor for corneal infection development 1
- For metallic foreign bodies, assess for rust ring formation and ensure complete removal 1
- Instruct patients to return immediately for worsening pain or vision, increasing redness, discharge, or persistent foreign body sensation 1
When to Obtain Cultures
For corneal foreign bodies with associated infiltrates, cultures are recommended when 3:
- Central, large infiltrate (within 3 mm of center and ≥2 mm in size) with significant stromal involvement or melting
- ≥1+ cells in anterior chamber
- History of corneal surgery or trauma with organic matter
- Multiple corneal infiltrates or atypical features