What is the volume per dose of amoxicillin (amoxicillin) suspension in milliliters (mL)?

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Amoxicillin Suspension Volume Per Dose

Amoxicillin oral suspension is available in two concentrations (125 mg/5 mL and 250 mg/5 mL), meaning each dose is 5 mL when using the standard concentration formulations. 1

Standard Suspension Volumes

The FDA-approved amoxicillin oral suspension provides the following volumes per dose based on concentration:

  • 125 mg/5 mL suspension: Each 5 mL contains 125 mg of amoxicillin 1
  • 250 mg/5 mL suspension: Each 5 mL contains 250 mg of amoxicillin 1

Key Clinical Considerations

The volume administered depends on the prescribed dose and the concentration of suspension used. For example, if a child requires 250 mg of amoxicillin:

  • Using 125 mg/5 mL suspension: administer 10 mL 1
  • Using 250 mg/5 mL suspension: administer 5 mL 1

Sodium Content

Each formulation contains different sodium amounts per 5 mL dose:

  • 125 mg/5 mL suspension: 0.11 mEq (2.51 mg) sodium per 5 mL 1
  • 250 mg/5 mL suspension: 0.15 mEq (3.36 mg) sodium per 5 mL 1

Important Pitfalls to Avoid

Always verify which concentration of suspension is being dispensed before calculating the volume to administer. The same milligram dose requires different volumes depending on suspension concentration. 1 Confusion between concentrations is a common source of dosing errors in pediatric patients.

Amoxicillin can be taken without regard to meals, though administration with food may improve gastrointestinal tolerability. 1 This flexibility allows dosing to be timed for optimal adherence rather than being restricted by meal schedules.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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