What Could Be Causing Your Pain?
Your pain requires immediate systematic evaluation to exclude life-threatening conditions first, then identify the specific cause based on location, character, timing, and associated symptoms.
Critical Life-Threatening Causes to Rule Out First
You need urgent evaluation if your pain has any of these features:
- Chest pain with shortness of breath, rapid heart rate - Could indicate pulmonary embolism, which presents with dyspnea, pleuritic chest pain, tachycardia, and tachypnea 1
- Sudden "ripping" chest pain radiating to the back - Suggests aortic dissection, with pulse differences between arms in 30% of cases 1
- Sharp chest pain that improves sitting forward, worsens lying down - May indicate pericarditis, which shows widespread ST-elevation with PR depression on ECG 1
- Chest pain with fever, productive cough - Could be pneumonia with pleuritic pain, regional dullness to percussion, and possible friction rub 1
- Sudden chest pain with absent breath sounds on one side - Classic for pneumothorax, characterized by dyspnea, pleuritic pain, and hyperresonant percussion 1
A critical pitfall: 13% of patients with sharp, pleuritic chest pain actually have acute myocardial ischemia, and 7% of patients with reproducible chest wall tenderness have acute coronary syndrome 1, 2. Never assume sharp pain or tenderness on palpation excludes cardiac disease.
Common Non-Life-Threatening Causes
Musculoskeletal Pain (Most Common)
- Costochondritis/Tietze syndrome - Tenderness of the costochondral joints on palpation, inflammation of cartilage connecting ribs to sternum 3, 4
- Muscle strain or spasm - Particularly pectoral muscles, worsens with movement 3, 4
- Rib fracture - Most common in ribs 3-8, presents with localized pain worsening with breathing or palpation 4
- Nerve entrapment - Especially the lateral cutaneous branch of the third intercostal nerve 3, 4
Breast Pain (If Female)
- Cyclical mastalgia - Bilateral, diffuse, related to menstrual cycle, affects women in their 30s, spontaneous resolution in 14-20% within 3 months 3
- Noncyclical mastalgia - Unilateral, focal, precisely localizable, more common in women in their 40s, inflammatory rather than hormonal 3
- Mastitis or breast abscess - Focal pain preceding induration, redness, warmth, and fever 3
Gastrointestinal Causes
- Gastroesophageal reflux, peptic ulcer disease, esophageal disorders - Account for 10-20% of chest pain in outpatients 4
- Gallbladder pathology - Can refer pain to chest area 3
Other Causes
- Herpes zoster - Dermatomal distribution pain triggered by touch, with characteristic unilateral rash 1
- Fibromyalgia or fibromyositis - Widespread musculoskeletal pain 3
Essential Initial Evaluation
You need these tests immediately if presenting with acute pain:
- ECG within 10 minutes - To identify STEMI, pericarditis patterns, or pulmonary embolism signs 1
- Chest X-ray - To evaluate for pneumothorax, pneumonia, pleural effusion, or widened mediastinum 1
- Cardiac troponin - Measured as soon as possible to exclude myocardial injury 1
Specific Features That Guide Diagnosis
Pain Character
- Sharp, stabbing, "knifelike" worsening with breathing - Pleuritic pain from pleural inflammation, pneumonia, or pulmonary embolism 1, 2
- Pressure or heaviness - More typical of anginal pain from coronary artery disease 2
- Creaking leather sound with breathing - Pleural friction rub indicating pleural inflammation 2
Pain Location
- Subareolar or nipple area, lower inner breast - Noncyclical mastalgia requiring evaluation to exclude breast lesion 3
- Lateral rib area - Rib fracture, costochondritis, or nerve entrapment 4
- Reproducible with chest wall palpation - Suggests musculoskeletal origin but does NOT exclude serious pathology 1
Associated Symptoms
- Fever - Pneumonia, mastitis, or pericarditis 1
- Shortness of breath - Pulmonary embolism, pneumothorax, or heart failure 1
- Redness, warmth, swelling - Mastitis or cellulitis 3
Immediate Action Required
Seek emergency care immediately if you have:
- Chest pain with shortness of breath, rapid heart rate, or sweating 1
- Sudden severe chest pain radiating to back 1
- Chest pain with weakness, slurred speech, or facial swelling 5
- Chest pain with fever and productive cough 1
Pain Management While Determining Cause
For non-emergent musculoskeletal pain:
- Ibuprofen - Use at lowest effective dose for shortest time needed; avoid if history of ulcers, bleeding problems, or heart disease 5
- Acetaminophen - Stop and seek medical attention if pain worsens or lasts more than 10 days 6
Critical warning: Do not use pain relief as a diagnostic test. Nitroglycerin response does not confirm or exclude myocardial ischemia 1.