Symptoms of Montair LC Kids Overdose
In the event of Montair LC Kids (montelukast + levocetirizine) overdose, the most frequently occurring symptoms include abdominal pain, somnolence, thirst, headache, vomiting, and psychomotor hyperactivity, though the majority of overdose cases have been asymptomatic. 1
Montelukast Component Overdose Symptoms
The montelukast component has demonstrated a remarkably safe overdose profile based on FDA drug labeling data:
- Most overdose cases are asymptomatic - the majority of reported overdoses produced no adverse experiences 1
- Abdominal pain is among the most common symptoms when they do occur 1
- Somnolence (drowsiness) may develop 1
- Thirst has been reported 1
- Headache can occur 1
- Vomiting may be present 1
- Psychomotor hyperactivity (increased restlessness and activity) 1
The FDA reports that montelukast has been studied at doses up to 200 mg/day for 22 weeks and up to 900 mg/day for approximately one week without clinically important adverse experiences in adults 1. Post-marketing overdose reports include doses as high as 1000 mg, with clinical findings consistent with the known safety profile 1.
Levocetirizine Component Overdose Symptoms
While specific overdose data for levocetirizine in the provided evidence is limited, antihistamine overdoses typically present with:
- Somnolence and sedation - this is the primary concern with antihistamine overdose
- Potential for paradoxical agitation in children, though this is more common with first-generation antihistamines
Management Approach
Employ usual supportive measures including removal of unabsorbed material from the gastrointestinal tract, clinical monitoring, and supportive therapy as required 1:
- Remove unabsorbed drug from the gastrointestinal tract if presentation is early 1
- Institute clinical monitoring for symptom development 1
- Provide supportive therapy as needed based on symptoms 1
- No specific antidote exists for either component 1