What is the indication for Lord's fundoplication in patients with Gastroesophageal Reflux Disease (GERD)?

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Lord's Fundoplication for GERD

Clarification: Lord's Fundoplication Does Not Exist as a Standard Procedure

There is no recognized surgical procedure called "Lord's fundoplication" in the treatment of gastroesophageal reflux disease. The established fundoplication techniques for GERD are Nissen (360° wrap), Toupet (270° posterior wrap), and Dor (anterior wrap) fundoplications 1, 2.


Standard Fundoplication Indications for GERD

If you are asking about laparoscopic fundoplication in general, the indications are:

Primary Indications

Laparoscopic fundoplication is indicated for patients with objectively documented pathologic GERD who have failed optimal medical therapy with proton pump inhibitors (PPIs), particularly those with PPI-responsive symptoms who develop untoward side effects or complications from PPI therapy 3, 2.

  • Surgery is recommended for patients with severe esophagitis (LA grade C or higher) that is uncontrollable with medical therapy 1
  • Patients with regurgitation-predominant GERD symptoms respond particularly well to mechanical anti-reflux procedures 4, 5
  • The procedure is appropriate for medically recalcitrant GERD with documented abnormal esophageal acid exposure on pH monitoring 6, 7

Essential Preoperative Requirements

Before proceeding with fundoplication, the following must be documented:

  • Objective confirmation of pathologic GERD through ambulatory pH or impedance-pH monitoring showing abnormal acid exposure 5, 2
  • High-resolution manometry confirming normal esophageal peristaltic function and excluding achalasia 1, 5
  • Complete endoscopic evaluation documenting presence/absence of erosive esophagitis, hiatal hernia size, and Barrett's esophagus 4, 5
  • Barium swallow to identify hiatus hernia, strictures, or short esophagus 1

Contraindications

Fundoplication should not be performed in:

  • Large hiatal hernias (>2 cm) without concurrent hernia repair 5
  • Esophageal motility disorders or impaired peristaltic function 5, 2
  • Achalasia or other primary esophageal motility disorders 1, 5
  • Lack of objective GERD confirmation (negative pH studies) 5

Surgical Technique Selection

Nissen Fundoplication (360° Wrap)

  • The Nissen fundoplication remains the gold standard for durable relief of GERD symptoms with an 80% success rate at 20-year follow-up 1, 2
  • This is the most commonly performed antireflux operation 8, 7
  • It provides superior long-term reflux control but carries higher risk of postoperative dysphagia 1

Toupet Fundoplication (270° Posterior Wrap)

  • The Toupet is an alternative with potentially lower rates of postoperative dysphagia, gas bloat syndrome, and inability to belch 1
  • It should be considered in patients with borderline esophageal motility or concerns about postoperative dysphagia 8, 6
  • The choice between total and partial fundoplication should be based on the quality of esophageal peristalsis documented by preoperative manometry 1

Hiatal Hernia Repair

  • Routine addition of an antireflux fundoplication is recommended when repairing large hiatal hernias, as omission leads to esophagitis in 28% and abnormal acid exposure in 39% of patients 9
  • Closure of the diaphragmatic hiatus using non-absorbable sutures is essential 1

Expected Outcomes

  • Heartburn and regurgitation are completely eliminated in 90% of patients 8
  • GERD symptoms are relieved in 93-95% of patients at intermediate and long-term follow-up 6, 7
  • Daily PPI intake after surgery drops to 8% 6
  • Laparoscopic approach has excellent safety with in-hospital mortality of 0.14% 1
  • Conversion to open surgery occurs in only 0.5-2% of cases 6, 7

Common Postoperative Issues

  • Dysphagia, early satiety, and bloating are typical in the immediate postoperative period but generally improve substantially within 4-8 weeks 8
  • Gas bloat syndrome and inability to vomit may persist in some patients 3
  • Reoperation rates range from 4-5% for complications including recurrent reflux or severe dysphagia 6, 7

References

Guideline

Management of LA Grade C Reflux Esophagitis with Small Sliding Hiatus Hernia

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Laparoscopic fundoplication for gastroesophageal reflux disease.

World journal of gastroenterology, 2014

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Endoscopic Fundoplication for Gastroesophageal Reflux Disease (GERD)

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Endoscopic Fundoplication for GERD: Insurance Approval Criteria

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Primary laparoscopic fundoplication in selected patients with gastroesophageal reflux disease.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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