What is the code for an MRI of the abdomen with Gadoxetate disodium that includes dynamic, multi-phase imaging, plus diffusion-weighted imaging?

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CPT Code for MRI Abdomen with Gadoxetate Disodium Including Dynamic Multi-Phase and Diffusion-Weighted Imaging

The appropriate CPT code is 74183 (MRI abdomen with contrast material, including dynamic multi-phase imaging and diffusion-weighted imaging when performed).

Code Selection Rationale

CPT 74183 specifically encompasses MRI of the abdomen with intravenous contrast that includes dynamic multi-phase imaging plus diffusion-weighted imaging (DWI), making it the single comprehensive code for this examination. 1

Key Components Included in 74183

  • Dynamic multi-phase imaging with at least two phases (late arterial and portal venous phases minimum) is mandatory for proper liver lesion characterization 2, 1

  • Diffusion-weighted imaging (DWI) is explicitly included when performed as part of the protocol 2, 1

  • Gadoxetate disodium (Eovist) administration as the hepatobiliary contrast agent 2

  • Hepatobiliary phase imaging at approximately 20 minutes post-injection, which is inherent to gadoxetate protocols 2

Protocol Requirements for Proper Coding

Essential Dynamic Phases

  • Late arterial phase (approximately 15-25 seconds post-injection) captures maximal lesion enhancement 2, 1

  • Portal venous phase (approximately 60 seconds post-injection) is required per LI-RADS criteria 2

  • Hepatobiliary phase (approximately 20 minutes with gadoxetate) provides functional hepatocyte assessment 2

Technical Specifications

  • Gadoxetate disodium dose: 0.25 mmol/mL (standard hepatobiliary agent dosing) 3

  • T1-weighted volumetric sequences are typically used for dynamic phases 3

  • DWI sequences with apparent diffusion coefficient (ADC) mapping improve differentiation of benign versus malignant lesions 2

Clinical Context Supporting This Code

Superior Diagnostic Performance

  • Gadoxetate-enhanced MRI with dynamic phases plus DWI achieves 87-91% accuracy for liver lesion characterization 2

  • Addition of DWI to dynamic sequences improves accuracy to 93% with 97% sensitivity for distinguishing HCC from dysplastic nodules 2

  • This protocol provides 95-99% diagnostic accuracy compared to 71% with CT alone 1

Why This Specific Combination Matters

  • Dynamic multi-phase imaging alone (without DWI) has lower sensitivity for small lesions <2 cm 2

  • DWI addition significantly improves detection and characterization, particularly for lesions <3 cm where mean ADC values differentiate benign from malignant 2

  • Gadoxetate specifically (versus extracellular agents) increases sensitivity from 46-59% to 68-80% for lesion detection 2

Common Coding Pitfalls to Avoid

Do Not Separately Code

  • Do not bill separately for DWI when it's part of the comprehensive liver protocol - it's included in 74183 1

  • Do not use 74181 (MRI abdomen without contrast) - this lacks the essential contrast phases needed 1

  • Do not use 74182 (MRI abdomen without and with contrast) unless the protocol specifically requires pre-contrast T1 sequences for comparison, though this is typically unnecessary with gadoxetate 4

Documentation Requirements

  • Ensure radiology report documents all acquired phases: arterial, portal venous, hepatobiliary, and DWI sequences 2, 1

  • Specify gadoxetate disodium by name in the protocol to justify the extended imaging time for hepatobiliary phase 2

  • Document clinical indication requiring this comprehensive protocol (e.g., liver lesion characterization, HCC surveillance in cirrhosis) 2

Alternative Scenarios

If Hepatobiliary Phase Not Performed

  • Use 74182 if only standard dynamic phases (arterial/portal venous) with extracellular gadolinium agent are performed without hepatobiliary phase 1

If DWI Not Performed

  • Still use 74183 if dynamic multi-phase imaging with gadoxetate is performed, as DWI is listed as "when performed" in the code descriptor 1

References

Guideline

Liver Lesion Evaluation with MRI

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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