Immediate Treatment for Bell's Palsy
Start oral corticosteroids immediately within 72 hours of symptom onset—this is the single most important intervention that significantly improves facial nerve recovery. 1
First-Line Treatment Protocol
Prescribe one of these corticosteroid regimens: 1, 2
- Prednisolone 50 mg daily for 10 days, OR
- Prednisone 60 mg daily for 5 days, then taper by 10 mg daily over the next 5 days 1, 2
The evidence is compelling: 83% of patients recover at 3 months with prednisolone versus only 63.6% with placebo, and 94.4% recover at 9 months versus 81.6% with placebo. 2 This represents a strong recommendation from the American Academy of Otolaryngology-Head and Neck Surgery for all patients 16 years and older. 1, 2
Combination Therapy Decision
Consider adding antiviral therapy to corticosteroids for patients with severe paralysis or those presenting early (within 72 hours). 1, 3
If adding antivirals: 4
- Valacyclovir 1 g three times daily for 7 days, OR
- Acyclovir 400 mg five times daily for 10 days 4
One study demonstrated 96.5% complete recovery with combination therapy versus 89.7% with steroids alone. 1 However, never prescribe antivirals as monotherapy—this is ineffective and explicitly not recommended. 1, 2
Critical Eye Protection (Implement Immediately)
For any patient with impaired eye closure, start aggressive eye protection immediately to prevent corneal damage: 1, 2
- Lubricating ophthalmic drops frequently throughout the day 2
- Ophthalmic ointment at bedtime (more effective moisture retention but causes temporary vision blurring) 2
- Eye patching or taping at night (requires careful instruction on proper technique to avoid corneal abrasion) 2
- Sunglasses for outdoor protection 2
- Moisture chambers using polyethylene covers for nighttime 2
Refer immediately to ophthalmology if severe lagophthalmos is present. 2
Essential Diagnostic Exclusions
Before diagnosing Bell's palsy, confirm: 2
- Acute onset within 72 hours 2
- Unilateral facial weakness involving the forehead (distinguishes from central causes) 2, 4
- No other cranial nerve involvement 2
- No bilateral weakness (suggests alternative diagnosis) 2
Do NOT order routine laboratory tests or imaging for typical presentations—diagnosis is clinical. 1, 2
Common Pitfalls to Avoid
- Delaying treatment beyond 72 hours dramatically reduces effectiveness 1, 3
- Using antiviral monotherapy is completely ineffective 1, 2
- Failing to provide adequate eye protection can lead to permanent corneal damage 1, 2
- Missing atypical features that require imaging (second paralysis on same side, isolated branch paralysis, other cranial nerve involvement) 2
Follow-Up Requirements
Reassess or refer to a facial nerve specialist if: 1, 2
- New or worsening neurologic findings develop at any point 1, 2
- Ocular symptoms develop 1, 2
- Incomplete facial recovery persists at 3 months after symptom onset 1, 2
Special Population Considerations
Children: Have better prognosis with up to 90% spontaneous recovery, but evidence for steroid benefit is less conclusive—consider treatment on individualized basis with caregiver involvement. 2, 4
Pregnant women: Treat with oral corticosteroids using careful individualized risk-benefit assessment. 2
Elderly patients (>60 years): May benefit more from combination therapy—one study showed 100% complete recovery in treated elderly patients versus 42% in untreated controls. 5