What are the current evidence-based recommendations for the management of diabetes mellitus?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: November 24, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

I cannot provide a Vancouver-format reference for a single clinical study meeting your specific criteria (original research from the past 6-12 months in NEJM/Lancet on diabetes management) because the evidence provided does not contain such a study.

What the Evidence Contains

The materials provided consist primarily of:

  • Guidelines from 2011-2023 focusing on laboratory diagnosis and general diabetes care standards 1
  • Cardiovascular prevention guidelines from 2011 that tangentially address diabetes 1
  • Guideline summaries from Praxis Medical Insights 2, 3
  • FDA drug labels for metformin 4
  • Review articles and narrative reviews from 2022-2024, not original research 5, 6, 7
  • Older research from 2002 8, 9

Why This Matters for Your Request

None of these sources represent original clinical research published in the past 6-12 months in high-impact journals like NEJM or Lancet. The most recent guideline is from 2023 1, but guidelines synthesize existing evidence rather than present new clinical trial data. The research articles provided are either reviews 5, 6, 7 or dated from 2002 8, 9.

What You Need Instead

To obtain a Vancouver-format reference for a clinically significant original research study on diabetes management from NEJM, Lancet, JAMA, or similar journals from the past 6-12 months, you would need to:

  • Search PubMed directly using filters for publication date (last 6-12 months), article type (clinical trial, randomized controlled trial), and journal
  • Check the specific journal websites (NEJM.org, TheLancet.com) for their diabetes-related original research
  • Review recent landmark trials such as cardiovascular outcome trials for newer diabetes medications (SGLT2 inhibitors, GLP-1 receptor agonists)

The evidence base provided here is valuable for understanding current management recommendations 2, 3 but does not contain the specific type of citation you requested.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Diabetes Management Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Diabetes Management Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Recent Updates to Clinical Practice Guidelines for Diabetes Mellitus.

Endocrinology and metabolism (Seoul, Korea), 2022

Research

Diabetes mellitus.

Clinics in podiatric medicine and surgery, 2002

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.