Differential Diagnosis for Positive Filariasis AB IGG4 Test
Given the patient's residence in Oklahoma and Missouri, and the potential for cross-reactivity with other parasitic infections, the following differential diagnoses are considered:
- Single most likely diagnosis
- Toxocariasis: This parasitic infection, caused by the Toxocara roundworm, is common in the United States and can cause cross-reactivity with filariasis tests. The patient's residence in Oklahoma and Missouri, where toxocariasis is prevalent, supports this diagnosis.
- Other Likely diagnoses
- Hookworm infection: Hookworms are endemic in the southern United States, and infections can occur through contact with contaminated soil. Cross-reactivity with filariasis tests is possible, making this a plausible diagnosis.
- Strongyloidiasis: This parasitic infection, caused by the Strongyloides stercoralis nematode, is found in the southern United States and can cause cross-reactivity with filariasis tests.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Chagas disease: Although rare in the United States, Chagas disease can be found in the southern and western regions. It is caused by the Trypanosoma cruzi parasite and can be life-threatening if left untreated. Cross-reactivity with filariasis tests is possible, making it essential to consider this diagnosis.
- Leishmaniasis: This parasitic infection, caused by the Leishmania parasite, is rare in the United States but can be found in some regions. It can cause severe symptoms if left untreated, and cross-reactivity with filariasis tests is possible.
- Rare diagnoses
- Trichinosis: This parasitic infection, caused by the Trichinella spiralis nematode, is rare in the United States but can occur through consumption of undercooked or raw meat. Cross-reactivity with filariasis tests is possible, although it is an unlikely diagnosis.
- Cysticercosis: This parasitic infection, caused by the Taenia solium tapeworm, is rare in the United States but can occur through consumption of contaminated food or water. Cross-reactivity with filariasis tests is possible, although it is an unlikely diagnosis.