What are the symptoms of a Cimex lectularius (bed bug) bite?

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Last updated: April 1, 2025 • View editorial policy

From the Research

Bedbug bites should be treated with symptomatic relief, including topical pramoxine and oral antihistamines to alleviate pruritus, and topical corticosteroids for significant eruptions, as recommended by the most recent study 1. To manage bedbug bites, it is essential to:

  • Wash the affected area with soap and water
  • Apply an over-the-counter hydrocortisone cream (1%) or calamine lotion to reduce itching
  • Take an antihistamine like diphenhydramine (Benadryl) 25-50mg every 4-6 hours to control itching
  • Apply ice packs to reduce swelling in severe reactions Most bites heal within 1-2 weeks without medical attention, but it is crucial to avoid scratching to prevent secondary infections. If signs of infection develop, such as increasing redness, warmth, swelling, or pus, medical attention should be sought. To eliminate bedbugs from the home, a combination of nonchemical and chemical interventions is recommended, including:
  • Keeping affected areas clean and free of clutter
  • Vacuuming mattresses and furniture
  • Washing linens with hot water
  • Caulking wall holes and cracks where bugs can hide
  • Proper disposal of highly infested items
  • Placement of bed bug traps/interceptors at the base of beds and furniture
  • Consideration of professional pest control services, as suggested by 1 and supported by 2 and 3.

References

Research

Bed Bug Infestation: An Updated Review.

Current pediatric reviews, 2024

Research

Bedbugs: how to diagnose and manage cases of infestations.

Clinical and experimental dermatology, 2023

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.